Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00818Esomeprazole strontium--
BADD_D00819Estazolam--
BADD_D00821Estradiol--
BADD_D00831Estrogens--
BADD_D00832Estrogens conjugated synthetic a--
BADD_D00835Estrone sulfate--
BADD_D00844Ethinyl estradiol--
BADD_D00849Etidronic acid--
BADD_D00850Etodolac--
BADD_D00852Etonogestrel--
BADD_D00853Etophos--
BADD_D00854Etoposide--
BADD_D00855Etoposide phosphate--
BADD_D00856Etoricoxib--
BADD_D00857Etravirine--
BADD_D00858Everolimus0.011925%
BADD_D00861Exemestane--
BADD_D00862Exenatide--
BADD_D00863Extendin-4--
BADD_D00864Ezetimibe--
BADD_D00865Ezogabine--
BADD_D00868Famciclovir--
BADD_D00869Famotidine0.000222%
BADD_D00870Febuxostat--
BADD_D00871Felbamate--
BADD_D00872Felodipine--
BADD_D00873Fenofibrate--
BADD_D00874Fenofibric acid--
BADD_D00875Fenoldopam--
BADD_D00876Fenoldopam mesylate--
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