Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.0010.014848%
Abdominal pain07.01.05.0020.059393%
Abdominal pain lower07.01.05.0100.010311%Not Available
Abdominal pain upper07.01.05.0030.037533%
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Abnormal weight gain14.03.02.0100.002062%Not Available
Abortion18.01.01.0010.002887%Not Available
Abortion missed18.01.01.0020.001237%Not Available
Abortion spontaneous18.01.04.0010.072179%Not Available
Abscess11.01.08.0010.001650%Not Available
Abscess bacterial11.02.01.0270.000825%Not Available
Acne23.02.01.0010.046194%Not Available
Affective disorder19.04.04.0010.005362%Not Available
Aggression19.05.01.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Alopecia23.02.02.0010.032584%
Amenorrhoea05.05.01.002; 21.01.02.0010.194677%
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Anaesthesia17.02.07.0020.000825%Not Available
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Anger19.04.02.0010.006187%Not Available
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema10.01.05.009; 23.04.01.001--Not Available
Ankle fracture12.04.01.005; 15.08.03.005--
Anxiety19.06.02.0020.044132%
Arterial thrombosis24.01.01.0020.000825%Not Available
Arthralgia15.01.02.001--
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