Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fenoldopam
Drug ID BADD_D00875
Description A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Indications and Usage For the in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function.
Marketing Status Prescription; Discontinued
ATC Code C01CA19
DrugBank ID DB00800
KEGG ID D07946
MeSH ID D018818
PubChem ID 3341
TTD Drug ID D0R6BI
NDC Product Code Not Available
Synonyms Fenoldopam | Fenoldopam Hydrobromide | Hydrobromide, Fenoldopam | SK&F-82526 | SK&F 82526 | SK&F82526 | SKF-82526 | SKF 82526 | SKF82526 | SKF-82526J | SKF 82526J | SKF82526J | SK&F-82526J | SK&F 82526J | SK&F82526J | Corlopam | Fenoldopam Mesylate
Chemical Information
Molecular Formula C16H16ClNO3
CAS Registry Number 67227-56-9
SMILES C1CNCC(C2=CC(=C(C(=C21)Cl)O)O)C3=CC=C(C=C3)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Angina pectoris02.02.02.002; 24.04.04.002--
Anxiety19.06.02.002--
Back pain15.03.04.005--
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Cardiac failure02.05.01.001--
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dyspnoea02.01.03.002; 22.02.01.004--
Electrocardiogram T wave inversion13.14.05.007--Not Available
Extrasystoles02.03.02.003--Not Available
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Gastrointestinal pain07.01.05.005--
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypokalaemia14.05.03.002--
Hypotension24.06.03.002--
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia17.15.03.002; 19.02.01.002--
Leukocytosis01.02.01.002--
Muscle spasms15.05.03.004--
Myocardial infarction02.02.02.007; 24.04.04.009--
Myocardial ischaemia02.02.02.008; 24.04.04.010--Not Available
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