Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fenofibrate
Drug ID BADD_D00873
Description Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]
Indications and Usage For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
Marketing Status Prescription; Discontinued
ATC Code C10AB05
DrugBank ID DB01039
KEGG ID D00565
MeSH ID D011345
PubChem ID 3339
TTD Drug ID D07XGR
NDC Product Code 68180-746; 0378-3065; 0115-0522; 46708-555; 27241-117; 71335-0891; 0115-1523; 68071-2587; 13672-020; 13668-439; 62332-361; 70934-567; 27241-116; 62332-555; 42291-292; 66869-137; 51407-094; 68543-3189; 0074-3189; 0378-3066; 16714-741; 46708-086; 31722-596; 70934-508; 68180-745; 65862-769; 71610-027; 16714-163; 50090-3044; 0378-7100; 0904-6810; 60505-3120; 51407-204; 42385-950; 66064-1006; 71335-1286; 71205-366; 50090-5401; 68180-130; 55111-395; 27241-120; 68071-2540; 71205-949; 62559-461; 69238-1261; 31722-595; 62559-305; 0378-7101; 50090-5796; 0115-0511; 43975-305; 50268-313; 42858-067; 68071-4692; 0904-7128; 68071-4992; 70518-3370; 62332-554; 68382-269; 43547-430; 35561-347; 63304-901; 27437-109; 16714-162; 17337-0410; 69238-1262; 62332-351; 68294-0001; 70518-2907; 43975-444; 50090-1275; 63304-449; 62332-539; 55111-349; 68180-231; 70518-2947; 51407-205; 59651-203; 59651-201; 62332-085; 62332-350; 63187-681; 69844-008; 42385-935; 68071-4983; 63304-444; 65862-768; 69097-458; 70966-0021; 68788-7579; 68180-360; 68382-270; 13668-438; 72189-172; 68071-3114; 68071-4310; 68462-581; 50090-4121; 71205-050; 50090-5854; 46708-351; 59349-0018; 62559-306; 50090-1274; 71335-0741; 69097-894; 60687-629; 42858-200; 69097-895; 35561-345; 68084-835; 46708-085; 60687-618; 68071-4358; 0074-3173; 51079-608; 50090-5327; 68788-7932; 63629-7213; 13668-440; 51407-091; 51407-092; 35561-346; 60760-411; 62332-360; 50090-3887; 50090-3842; 69238-1263; 51079-599; 68071-1601; 68084-827; 63629-2505; 42291-290; 70934-638; 70518-0700; 42858-660; 27241-118; 11014-0132; 71205-190; 68071-4264; 42385-951; 50268-309; 71335-1292; 71335-1756; 59651-202; 63629-1514; 68012-490; 0115-1522; 50090-4957; 49452-3101; 70756-214; 69844-013; 0378-4390; 16714-739; 68071-4320; 42385-936; 68084-329; 46708-857; 68071-5101; 63629-1099; 0904-7161; 68180-232; 63187-760; 46708-554; 50090-4698; 50090-3373; 46708-350; 27437-108; 46708-084; 0615-8270; 62332-086; 68788-8106; 17337-0019; 70934-223; 50090-2899; 68071-4182; 66869-147; 16714-740; 68180-131; 63187-640; 60760-318; 45802-315; 50268-312; 43353-898; 68084-328; 43598-910; 68543-3173; 70756-215; 51407-090; 72189-026; 62332-538; 17337-0430; 69367-257; 68012-495; 46708-361; 68462-582; 68682-495; 62332-084; 60760-660; 63304-443; 42291-289; 43598-909; 70518-2768; 43547-431; 27437-107; 0115-0533; 62559-460; 70934-224; 55700-876; 68071-4991; 11722-065; 50090-5244; 65977-0074; 70934-591; 63629-1100; 45802-132; 0378-4391; 69844-012; 69367-254; 42858-454; 68788-7662; 69367-269; 63629-1101; 27241-119; 71335-0872; 68180-389; 68071-4289; 60505-3121; 71335-2016; 50090-4031; 69367-270; 68180-363; 43353-272; 63187-940; 68071-2369; 69844-009; 69097-459; 50090-3904; 68180-362; 27437-110; 68084-635; 63304-448; 69097-896; 42858-134; 50090-2546; 58175-0348; 71335-1701; 69238-1260; 46708-360; 0115-5511; 63304-900; 0115-5522; 11014-0131; 68788-7578; 43353-001; 43975-306; 50090-5158; 51407-093; 68180-361; 69367-268; 53747-033; 68682-490; 68462-580; 70518-2349; 68071-4988; 68788-7816; 70518-1988; 68180-388
Synonyms Fenofibrate | Phenofibrate | Procetofene | Procetofen | Apo-Feno-Micro | Apo Feno Micro | Apo-Fenofibrate | Apo Fenofibrate | CiL | Controlip | durafenat | Fenobeta | Fenofanton | Fenofibrat AbZ | Fenofibrat AL | Fenofibrat AZU | AZU, Fenofibrat | Fenofibrat Heumann | Heumann, Fenofibrat | Fenofibrat Hexal | Hexal, Fenofibrat | Fenofibrat Stada | Stada, Fenofibrat | fenofibrat von ct | Fenofibrat-ratiopharm | Fenofibrat ratiopharm | Fénofibrate MSD | Gen-Fenofibrate | Gen Fenofibrate | LF-178 | LF 178 | LF178 | Lipanthyl | Lipantil | Fenofibrat FPh | Lipidil | Secalip | Supralip | Fénofibrate Debat | Debat, Fénofibrate | Lipidil-Ter | Lipidil Ter | Liparison | Livesan | Lofibra | MTW-Fenofibrat | MTW Fenofibrat | Novo-Fenofibrate | Novo Fenofibrate | Nu-Fenofibrate | Nu Fenofibrate | PMS-Fenofibrate Micro | PMS Fenofibrate Micro | Tricor | Normalip | Antara Micronized Procetofen | Micronized Procetofen, Antara | Procetofen, Antara Micronized
Chemical Information
Molecular Formula C20H21ClO4
CAS Registry Number 49562-28-9
SMILES CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.000776%
Acne23.02.01.001--Not Available
Acute prerenal failure20.01.03.001; 24.06.02.0030.000173%Not Available
Agitation17.02.05.012; 19.06.02.001--
Alanine aminotransferase increased13.03.01.0030.000949%
Alopecia23.02.02.001--
Alveolitis22.01.01.001--Not Available
Alveolitis allergic10.01.03.008; 22.01.01.002--Not Available
Amblyopia06.02.01.001--Not Available
Amnesia17.03.02.001; 19.20.01.0010.000173%
Anaemia01.03.02.001--
Angina pectoris02.02.02.002; 24.04.04.0020.000431%
Angioedema10.01.05.009; 23.04.01.0010.000949%Not Available
Anorectal disorder07.03.01.001--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arteriosclerosis24.04.02.001--Not Available
Arthralgia15.01.02.0010.001122%
Arthritis15.01.01.001--
Arthropathy15.01.01.003--Not Available
Aspartate aminotransferase13.03.01.032--Not Available
Aspartate aminotransferase increased13.03.01.0060.000776%
Asthenia08.01.01.001--Not Available
Asthma10.01.03.010; 22.03.01.002--Not Available
Atrial fibrillation02.03.03.002--
Autoimmune hepatitis09.01.07.019; 10.04.09.0010.000259%Not Available
Back pain15.03.04.005--
Benign prostatic hyperplasia21.04.02.0010.000173%Not Available
Bladder pain20.02.02.001--Not Available
Blister12.01.06.002; 23.03.01.001--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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