Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Estazolam
Drug ID BADD_D00819
Description A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Indications and Usage For the short-term management of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings.
Marketing Status Prescription; Discontinued
ATC Code N05CD04
DrugBank ID DB01215
KEGG ID D00311
MeSH ID D004949
PubChem ID 3261
TTD Drug ID D0P2CK
NDC Product Code 0591-0744; 51862-074; 12828-0077; 51862-069; 0591-0745; 70954-480; 70954-481; 51862-073; 51862-070; 48087-0031
Synonyms Estazolam | Tasedan | ProSom | D-40TA | D40TA | Nuctalon
Chemical Information
Molecular Formula C16H11ClN4
CAS Registry Number 29975-16-4
SMILES C1C2=NN=CN2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Acne23.02.01.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Agranulocytosis01.02.03.001--Not Available
Amnesia17.03.02.001; 19.20.01.001--
Anxiety19.06.02.002--
Apathy19.04.04.002--Not Available
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Asthma10.01.03.010; 22.03.01.002--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Back pain15.03.04.005--
Body temperature increased13.15.01.001--Not Available
Breast swelling21.05.05.008--Not Available
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Chills08.01.09.001; 15.05.03.016--
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Cough22.02.03.001--
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diplopia06.02.06.002; 17.17.01.005--Not Available
Discomfort08.01.08.003--Not Available
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
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