Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Infusion site extravasation
ADR ID BADD_A06266
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.07      Administration site reactions
12.07.05      Infusion site reactions
12.07.05.008      Infusion site extravasation
08      General disorders and administration site conditions
08.02      Administration site reactions
08.02.05      Infusion site reactions
08.02.05.007      Infusion site extravasation
Description A disorder characterized by leakage of the infusion into the surrounding tissue. Signs and symptoms may include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site. [CTCAE] The escape of diagnostic or therapeutic material from the vessel into which it is introduced into the surrounding tissue or body cavity. [MeSH]
MedDRA Code 10064774
MeSH ID D005119
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Infusion site infiltration | Infusion site extravasation | Contrast media extravasation | Extravasation of Diagnostic and Therapeutic Materials | Extravasation of Diagnostic, Therapeutic Materials | Extravasation of Contrast Media | Contrast Media Extravasation
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00115Amiodarone0.000296%
BADD_D00121Amlodipine--
BADD_D00193Axitinib--
BADD_D00195Azathioprine--
BADD_D00203Azithromycin0.000021%
BADD_D00230Bendamustine0.001959%
BADD_D00284Bortezomib0.000437%
BADD_D00306Budesonide--
BADD_D00348Cangrelor0.000280%
BADD_D00364Carboplatin0.000280%
BADD_D00367Carfilzomib0.004958%
BADD_D00376Caspofungin--
BADD_D00405Ceftriaxone0.019609%
BADD_D00474Cisplatin0.000112%
BADD_D00482Clevidipine0.000228%
BADD_D00560Cytarabine0.000112%
BADD_D00581Daptomycin0.000248%
BADD_D00620Desoximetasone--
BADD_D00629Dexmedetomidine0.000732%
BADD_D00723Doxorubicin0.000414%
BADD_D00782Epinephrine0.000081%
BADD_D00788Epoprostenol0.000263%
BADD_D00854Etoposide0.000168%
BADD_D00890Ferumoxytol non-stoichiometric magnetite-
BADD_D00931Fluorouracil0.000993%
BADD_D00979Furosemide0.000014%
BADD_D00984Gadobutrol0.019206%
BADD_D01058Hemin-
BADD_D01117Ibandronic acid0.004466%
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