Drug Name |
Azathioprine |
Drug ID |
BADD_D00195 |
Description |
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.[L11214]
Azathiprine was granted FDA approval on 20 March 1968.[L11214] |
Indications and Usage |
Azathioprine is indicated to treat rheumatoid arthritis and prevent renal transplant rejection.[L11214] |
Marketing Status |
approved |
ATC Code |
L04AX01 |
DrugBank ID |
DB00993
|
KEGG ID |
D00238
|
MeSH ID |
D001379
|
PubChem ID |
2265
|
TTD Drug ID |
D07QCE
|
NDC Product Code |
62991-2189; 65649-231; 67877-492; 68084-229; 68382-120; 51407-182; 68382-118; 72789-129; 46014-1110; 70771-1141; 60219-1076; 60219-2036; 60219-2037; 68382-003; 48954-909; 51927-0071; 68682-241; 70518-3544; 70771-1140; 51927-2258; 54766-590; 65841-602; 12780-0300; 38779-0312; 66122-0009; 42291-063; 68462-502; 71610-124; 42291-071; 68682-231; 70771-1139; 15308-0732; 49452-0783; 67877-493; 51552-0779; 65649-241; 67877-494; 67877-495; 68382-119; 42973-143 |
UNII |
MRK240IY2L
|
Synonyms |
Azathioprine | Azothioprine | Imurel | Imuran | Immuran | Azathioprine Sodium | Sodium, Azathioprine | Azathioprine Sodium Salt | Azathioprine Sulfate |