Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Diabetic ketoacidosis
ADR ID BADD_A01252
ADR Hierarchy
05      Endocrine disorders
05.07      Diabetic complications
05.07.03      Diabetic complications NEC
05.07.03.001      Diabetic ketoacidosis
14      Metabolism and nutrition disorders
14.07      Diabetic complications
14.07.03      Diabetic complications NEC
14.07.03.001      Diabetic ketoacidosis
Description A life-threatening complication of diabetes mellitus, primarily of TYPE 1 DIABETES MELLITUS with severe INSULIN deficiency and extreme HYPERGLYCEMIA. It is characterized by KETOSIS; DEHYDRATION; and depressed consciousness leading to COMA. [MeSH]
MedDRA Code 10012671
MeSH ID D016883
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acidosis diabetic | Diabetes mellitus with ketoacidosis | Diabetes with ketoacidosis | Diabetic acidosis | Diabetic ketoacidosis | Ketoacidosis (diabetic) | Type I diabetes mellitus with ketoacidosis | Type II diabetes mellitus with ketoacidosis | Diabetic Ketoacidosis | Diabetic Acidosis | Ketoacidosis, Diabetic | Diabetic Ketoacidoses | Ketoacidoses, Diabetic | Ketosis, Diabetic | Acidosis, Diabetic | Acidoses, Diabetic | Diabetic Acidoses | Diabetic Ketosis | Diabetic Ketoses | Ketoses, Diabetic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00018Acarbose0.001084%
BADD_D00165Aripiprazole0.001228%
BADD_D00271Bicalutamide0.002812%
BADD_D00332Caffeine0.000092%
BADD_D00344Canagliflozin0.055139%
BADD_D00414Ceritinib0.000112%
BADD_D00488Clobazam0.000196%
BADD_D00578Dapagliflozin0.039157%
BADD_D00623Dexamethasone0.001380%
BADD_D00649Diazoxide--
BADD_D00765Empagliflozin0.064196%
BADD_D00932Fluoxetine--
BADD_D00981Gabapentin--
BADD_D01023Glimepiride0.000127%
BADD_D01159Insulin (human)--
BADD_D01160Insulin aspart--
BADD_D01167Interferon alfa-2b--
BADD_D01252Leflunomide0.000857%
BADD_D01258Leucovorin0.001239%
BADD_D01401Metformin0.000504%
BADD_D01476Mirtazapine0.000240%
BADD_D01599Olanzapine0.004041%
BADD_D01600Olanzapine pamoate--
BADD_D01656Paliperidone--
BADD_D01696Peginterferon alfa-2b--
BADD_D01831Prednisolone0.000350%
BADD_D01834Prednisone0.000085%
BADD_D01888Quetiapine0.000218%
BADD_D01951Risperidone--
BADD_D02029Sitagliptin0.000186%
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