Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Diazoxide
Drug ID BADD_D00649
Description A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
Indications and Usage Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Marketing Status approved
ATC Code C02DA01; V03AH01
DrugBank ID DB01119
KEGG ID D00294
MeSH ID D003981
PubChem ID 3019
TTD Drug ID D07WEP
NDC Product Code 51552-1582; 58159-039; 51927-0297; 14501-0096; 0254-1010; 45562-1740; 69575-4025; 0575-6200; 38779-0324; 52952-003; 38779-3184; 51927-2742; 62991-2857; 71052-664; 13517-100
UNII O5CB12L4FN
Synonyms Diazoxide | Proglycem | Hyperstat
Chemical Information
Molecular Formula C8H7ClN2O2S
CAS Registry Number 364-98-7
SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Abdominal pain07.01.05.002--
Ageusia07.14.03.003; 17.02.07.001---
Albuminuria20.02.01.001---
Anaemia01.03.02.0010.000329%
Angina pectoris02.02.02.002; 24.04.04.002--
Anxiety19.06.02.002--
Arrhythmia supraventricular02.03.03.001---
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001---
Azotaemia20.01.01.001---
Back pain15.03.04.005--
Blood creatinine decreased13.13.01.003---
Blood immunoglobulin G decreased13.06.05.001---
Blood urea increased13.13.01.006---
Body temperature increased13.15.01.001---
Bradycardia02.03.02.002---
Breast mass21.05.04.002---
Cardiac failure02.05.01.0010.000219%
Cardiac failure congestive02.05.01.0020.000439%-
Cataract06.06.01.001--
Cellulitis11.02.01.001; 23.11.02.004---
Cerebral ischaemia17.08.01.005; 24.04.06.003--
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.002---
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Choking sensation19.01.02.002; 22.12.03.004---
Condition aggravated08.01.03.0040.000329%-
Confusional state17.02.03.005; 19.13.01.001--
Conjunctival haemorrhage06.07.01.001; 24.07.05.001---
Constipation07.02.02.001--
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