Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Diazoxide
Drug ID BADD_D00649
Description A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
Indications and Usage Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Marketing Status Prescription; Discontinued
ATC Code C02DA01; V03AH01
DrugBank ID DB01119
KEGG ID D00294
MeSH ID D003981
PubChem ID 3019
TTD Drug ID D07WEP
NDC Product Code 38779-0324; 0575-6200; 58159-039; 52952-003; 69575-4025; 62991-2857; 49452-2541; 51927-2742; 38779-3184; 71052-664; 0254-1010; 13517-100; 14501-0096; 45562-1740; 51552-1582
Synonyms Diazoxide | Proglycem | Hyperstat
Chemical Information
Molecular Formula C8H7ClN2O2S
CAS Registry Number 364-98-7
SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Ageusia07.14.03.003; 17.02.07.001--Not Available
Albuminuria20.02.01.001--Not Available
Anaemia01.03.02.0010.000253%
Angina pectoris02.02.02.002; 24.04.04.002--
Anxiety19.06.02.002--
Arrhythmia supraventricular02.03.03.001--Not Available
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Azotaemia20.01.01.001--Not Available
Back pain15.03.04.005--
Blood creatinine decreased13.13.01.003--Not Available
Blood immunoglobulin G decreased13.06.05.001--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Breast mass21.05.04.002--Not Available
Cardiac failure02.05.01.0010.000168%
Cardiac failure congestive02.05.01.0020.000969%Not Available
Cataract06.06.01.001--
Cellulitis11.02.01.001; 23.09.01.001--Not Available
Cerebral ischaemia17.08.01.005; 24.04.06.003--
Chest discomfort02.02.02.009; 08.01.08.019; 22.02.08.001--Not Available
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Choking sensation19.01.02.002; 22.02.05.002--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Conjunctival haemorrhage06.07.01.001; 24.07.05.001--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
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