Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Aripiprazole
Drug ID BADD_D00165
Description Aripiprazole is an atypical antipsychotic orally indicated for treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's[Label]. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania[Label]. Aripiprazole exerts its effects through agonism of dopaminic and 5-HT1A receptors and antagonism of alpha adrenergic and 5-HT2A receptors[Label,A4393]. Aripiprazole was given FDA approval on November 15, 2002[L6136].
Indications and Usage For the treatment of schizophrenia and related psychotic disorders.
Marketing Status Prescription; Discontinued
ATC Code N05AX12
DrugBank ID DB01238
KEGG ID D01164
MeSH ID D000068180
PubChem ID 60795
TTD Drug ID D0H3HM
NDC Product Code 48433-120; 59148-007; 68554-0095; 62332-099; 60505-2675; 59148-010; 76282-045; 68382-439; 27241-056; 71335-1903; 31722-829; 63629-7017; 46708-256; 16714-787; 60505-2674; 17856-0570; 59651-110; 43598-554; 70518-3380; 48433-115; 65862-662; 65862-680; 50090-4817; 65162-896; 33342-123; 70518-2565; 68788-7162; 13668-219; 76282-049; 71335-1980; 60429-451; 0904-6511; 0904-6656; 31722-820; 50370-0009; 48433-117; 16714-145; 50090-4160; 68554-0020; 55289-251; 70934-662; 59148-030; 43353-148; 46602-0045; 67877-432; 63629-7003; 46708-260; 68071-5062; 50370-0044; 70518-2508; 71335-1893; 42043-401; 27241-052; 50228-325; 68788-7733; 50090-4800; 46602-1031; 63739-413; 72865-185; 43547-304; 0904-6510; 43598-966; 59148-034; 70771-1454; 43547-303; 71335-0412; 27241-053; 60687-157; 29300-176; 43598-968; 76282-048; 43598-558; 59116-2901; 70771-1451; 46602-1029; 59148-018; 68382-083; 67877-433; 43547-306; 70518-1303; 50228-477; 69452-339; 68788-7808; 16729-279; 65162-902; 63415-0085; 70518-2765; 59148-011; 50228-324; 27241-054; 12828-0088; 70771-1456; 29300-178; 50090-5840; 67877-434; 43598-970; 50228-478; 62332-100; 50090-5839; 33342-126; 60505-2677; 46602-1032; 46602-0010; 31722-827; 72865-153; 72865-181; 53104-7628; 59148-045; 43598-967; 70518-2806; 46602-0006; 68788-7006; 46602-0026; 59148-029; 43598-555; 64220-112; 70518-2950; 33342-124; 50228-329; 70518-2584; 50090-4863; 16714-788; 60687-168; 70518-2869; 60505-2673; 13668-221; 43547-305; 43353-140; 72865-154; 16714-783; 72865-184; 33342-127; 62332-098; 71335-1935; 65862-666; 13668-216; 16729-280; 43353-180; 68382-085; 29300-179; 16714-141; 63629-6999; 65162-899; 65862-661; 43598-969; 0904-6514; 70518-2580; 16714-144; 70518-2567; 70518-2825; 70518-2736; 16714-146; 46602-0007; 66689-735; 58032-2005; 59148-072; 13668-217; 60429-446; 59148-032; 63187-965; 31722-830; 71335-1364; 65372-1121; 62332-097; 63739-070; 70518-2515; 16714-785; 50228-328; 70518-2536; 72865-183; 62332-101; 70518-2557; 0615-8375; 65862-663; 72865-182; 33342-122; 60505-2676; 43598-556; 71335-1682; 46602-0072; 50090-3941; 46602-0009; 43598-559; 46708-259; 68382-082; 50090-4936; 65691-0052; 43547-302; 46602-0008; 71205-480; 43598-965; 68382-084; 60429-449; 43547-307; 71335-1832; 71335-1515; 17856-0110; 50370-0055; 59148-006; 53747-031; 50228-327; 60505-3075; 50268-088; 70518-1263; 70518-2820; 13668-218; 50228-476; 72865-158; 50090-4665; 16729-278; 16714-786; 59148-008; 70518-2897; 72761-020; 68788-8089; 31722-819; 68788-7076; 65862-664; 70518-3011; 60687-213; 46602-0011; 72865-157; 29300-180; 76072-1002; 70518-2921; 46602-1030; 16729-282; 62332-102; 76282-047; 65841-140; 71335-1688; 70771-1455; 71335-1513; 46708-254; 48433-119; 60429-450; 65162-898; 60505-0404; 43353-147; 59148-031; 63739-074; 70771-1452; 46708-258; 0904-6509; 46708-255; 65162-897; 50268-091; 27241-051; 59148-019; 46602-1034; 76282-046; 46602-1033; 12658-0576; 0615-8259; 48433-118; 72865-155; 50228-480; 62332-103; 68788-7063; 0904-6512; 27241-055; 63629-7108; 50268-089; 53808-1101; 63739-078; 70518-3004; 68382-086; 70518-1421; 72865-180; 70518-2827; 50268-092; 16729-283; 66603-706; 68071-2394; 69452-338; 16729-281; 12658-0577; 70518-2514; 67877-431; 72865-156; 49706-1889; 68788-7749; 65862-665; 50268-087; 70518-2958; 69037-0058; 50228-475; 33342-125; 58623-0127; 63739-069; 70771-1453; 60429-447; 14445-019; 60429-448; 43598-557; 66603-705; 76282-044; 46602-0025; 50268-090; 71335-1687; 29300-177; 67835-0009; 31722-828; 71335-1892; 46708-261; 54838-570; 70518-0970; 60687-202; 71205-392; 63629-7774; 70518-3090; 67877-430; 16714-784; 29300-175; 70518-2974; 16714-143; 60687-179; 59148-033; 62332-104; 67877-435; 42043-400; 65096-0107; 13668-220; 16714-142; 46708-257; 50228-326; 48433-116; 65162-893; 59148-009; 50228-479; 0904-6513; 60687-191; 65162-901; 59116-2900; 71335-1711; 70518-2643
Synonyms Aripiprazole | 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone | Aripiprazol | Abilify | OPC 14597 | OPC-14597
Chemical Information
Molecular Formula C23H27Cl2N3O2
CAS Registry Number 129722-12-9
SMILES C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain lower07.01.05.010--Not Available
Abdominal pain upper07.01.05.003--
Abdominal tenderness07.01.05.004--Not Available
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Abnormal faeces07.01.03.001--Not Available
Abnormal sensation in eye06.01.01.0010.000572%Not Available
Abnormal weight gain14.03.02.0100.000381%Not Available
Abortion18.01.01.0010.003433%Not Available
Abortion missed18.01.01.0020.000381%Not Available
Abortion spontaneous18.01.04.0010.024793%Not Available
Accommodation disorder06.02.04.0010.000572%Not Available
Acne23.02.01.001--Not Available
Acute febrile neutrophilic dermatosis01.02.01.006; 23.03.03.0330.001335%Not Available
Acute myeloid leukaemia01.10.05.001; 16.01.05.001--Not Available
Acute myocardial infarction02.02.02.001; 24.04.04.001--Not Available
Acute psychosis19.03.01.0010.001526%Not Available
Acute respiratory failure14.01.04.004; 22.02.06.0010.000348%Not Available
Acute sinusitis11.01.13.012; 22.07.03.0130.000381%Not Available
Affective disorder19.04.04.0010.001716%Not Available
Aggression19.05.01.0010.016783%Not Available
Agitation17.02.05.012; 19.06.02.0010.017927%
Agoraphobia19.06.03.004--Not Available
Agranulocytosis01.02.03.001--Not Available
Akathisia17.01.02.002; 19.06.02.0060.022504%
Akinesia17.01.02.0030.000381%Not Available
Alanine aminotransferase abnormal13.03.01.0010.000381%Not Available
Alanine aminotransferase increased13.03.01.0030.003624%
The 1th Page    1 2 3 4 5    Next   Last    Total 42 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene