Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Quetiapine
Drug ID BADD_D01888
Description Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder.[L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [Clozapine] and [Olanzapine].[A2189]
Indications and Usage For the treatment of schizophrenia and related psychotic disorders.
Marketing Status Prescription; Discontinued
ATC Code N05AH04
DrugBank ID DB01224
KEGG ID D08456
MeSH ID D000069348
PubChem ID 5002
TTD Drug ID D0H7KF
NDC Product Code 0615-7987; 50090-2307; 65862-877; 63629-4939; 16714-456; 65862-876; 0310-0275; 71610-538; 0093-8166; 70518-0239; 0093-8164; 71093-139; 65862-874; 33342-136; 63629-2482; 71205-402; 63629-2480; 50228-383; 16729-146; 71335-0432; 63629-2481; 68001-181; 63629-7116; 68001-183; 50090-2831; 50090-2338; 71205-026; 0615-7988; 80425-0107; 0615-8118; 70518-0570; 71205-401; 70518-0752; 16714-457; 50090-2689; 68001-180; 70518-0229; 16729-147; 50090-3749; 16729-148; 0310-0274; 50228-381; 70518-0432; 68788-7412; 50090-5451; 50090-2830; 16729-150; 65862-873; 71093-135; 71093-137; 53002-1529; 68001-182; 0310-0282; 0615-7986; 16714-454; 71093-138; 71093-136; 80425-0143; 68788-7185; 70518-0289; 68788-7186; 0310-0279; 16714-455; 16714-452; 50228-382; 33342-135; 68001-185; 50228-380; 60687-371; 16729-149; 68788-7590; 53002-1516; 65862-875; 33342-134; 0310-0278; 0310-0281; 63629-2478; 60687-338; 50090-4788; 68788-7184; 0093-8162; 0310-0284; 68001-184; 16729-145; 63629-2479; 0615-8119; 16714-453; 33342-137; 70518-2828; 0093-8163; 0310-0283; 68071-4161; 60687-327; 0093-8165; 60687-360; 50228-384; 60687-349; 0093-2063; 60687-382; 0310-0271; 0310-0272; 0310-0280
Synonyms Quetiapine Fumarate | Ethanol, 2-(2-(4-dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)-, (E)-2-butenedioate (2:1) (salt) | Seroquel | ICI 204,636 | ICI-204636 | ICI204636 | ICI 204636 | Quetiapine | 2-(2-(4-dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol
Chemical Information
Molecular Formula C21H25N3O2S
CAS Registry Number 111974-69-7
SMILES C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Abdominal tenderness07.01.05.0040.000100%Not Available
Abnormal dreams17.15.02.001; 19.02.03.0010.001910%Not Available
Abnormal weight gain14.03.02.0100.002165%Not Available
Abortion missed18.01.01.0020.000764%Not Available
Abortion spontaneous18.01.04.001--Not Available
Accelerated hypertension24.08.01.0030.000255%Not Available
Accidental overdose12.06.03.002--Not Available
Accommodation disorder06.02.04.001--Not Available
Acidosis14.01.03.0020.001401%
Acne23.02.01.001--Not Available
Acoustic stimulation tests abnormal13.07.01.0040.000233%Not Available
Activated partial thromboplastin time prolonged13.01.02.001--
Acute abdomen07.01.06.0150.000382%Not Available
Acute hepatic failure09.01.03.0010.000365%Not Available
Acute myeloid leukaemia01.10.05.001; 16.01.05.001--Not Available
Acute psychosis19.03.01.0010.000255%Not Available
Acute respiratory distress syndrome22.01.03.0010.000698%
Acute respiratory failure14.01.04.004; 22.02.06.0010.000892%Not Available
Adrenal insufficiency05.01.02.001; 14.11.01.0040.000509%
Affective disorder19.04.04.0010.000637%Not Available
Aggression19.05.01.0010.008661%Not Available
Agitation17.02.05.012; 19.06.02.0010.018341%
Agitation neonatal17.02.05.028; 18.04.04.002; 19.06.02.0070.001274%Not Available
Agranulocytosis01.02.03.001--Not Available
Akathisia17.01.02.002; 19.06.02.0060.005604%
Akinesia17.01.02.0030.000382%Not Available
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