Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00614Desirudin--
BADD_D00616Desmopressin--
BADD_D00620Desoximetasone--
BADD_D00621Desvenlafaxine--
BADD_D00622Desvenlafaxine succinate--
BADD_D00626Dexchlorpheniramine--
BADD_D00627Dexchlorpheniramine maleate--
BADD_D00628Dexlansoprazole0.001009%
BADD_D00629Dexmedetomidine--
BADD_D00630Dexmedetomidine hydrochloride--
BADD_D00633Dexrazoxane--
BADD_D00634Dexrazoxane hydrochloride--
BADD_D00636Dextroamphetamine--
BADD_D00637Dextroamphetamine sulfate--
BADD_D00638Dextromethorphan--
BADD_D00648Diazepam--
BADD_D00649Diazoxide--
BADD_D00652Dichlorphenamide--
BADD_D00654Diclofenac epolamine--
BADD_D00655Diclofenac potassium--
BADD_D00656Diclofenac sodium--
BADD_D00659Dicyclomine0.000174%
BADD_D00660Dicyclomine hydrochloride--
BADD_D00662Diethylpropion--
BADD_D00663Diethylpropion hydrochloride--
BADD_D00666Diflunisal--
BADD_D00670Dihydrocodeine--
BADD_D00674Diltiazem--
BADD_D00675Diltiazem hydrochloride--
BADD_D00676Dimenhydrinate--
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