| Drug Name |
Dihydrocodeine |
| Drug ID |
BADD_D00670 |
| Description |
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.
It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis. It was marketed in 1911. |
| Indications and Usage |
Dihydrocodeine is used for the treatment of moderate to severe pain, including post-operative and dental pain [2]. It can also be used to treat chronic pain [1], breathlessness and coughing.
In heroin addicts, dihydrocodeine has been used as a substitute drug, in doses up to 2500mg/day to treat addiction. [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014322/]
|
| Marketing Status |
approved; illicit |
| ATC Code |
N02AA08 |
| DrugBank ID |
DB01551
|
| KEGG ID |
D07831
|
| MeSH ID |
C014481
|
| PubChem ID |
5284543
|
| TTD Drug ID |
D0T6RC
|
| NDC Product Code |
Not Available |
| UNII |
N9I9HDB855
|
| Synonyms |
dihydrocodeine | dihydrocodeine, (5alpha,6alpha,14alpha)-isomer | dihydrocodeine, (5alpha,6beta,14alpha)-isomer | paramol 118 | dihydrocodeine, (5alpha,6beta)-isomer | Rikodeine | Tiamon | Tosidrin | Contugesic | DF 118 | DHC Continus | DHC Mundipharma | Dicodin | dihydrocodeine acetate, (5alpha,6alpha)-isomer | dihydrocodeine bitartrate | dihydrocodeine hydrochloride, (5alpha,6alpha)-isomer | dihydrocodeine phosphate (1:1), (5alpha,6alpha)-isomer | dihydrocodeine tartrate (1:1), (5alpha,6alpha)-(R-(R*,R*))-isomer | dihydrocodeine tartrate (1:1), (5alpha,6beta)-(R-(R*,R*))-isomer | Paracodin | Paracodina | dihydrocodeine, thiocyanate salt (5alpha,6alpha)-isomer |
