Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Diethylpropion hydrochloride
Drug ID BADD_D00663
Description A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Indications and Usage Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Marketing Status approved; illicit
ATC Code A08AA03
DrugBank ID DB00937
KEGG ID D03801
MeSH ID D004053
PubChem ID 91442
TTD Drug ID D0B7OD
NDC Product Code 17337-0016; 43063-348; 71335-1779; 62135-488; 63187-621; 10920-600; 68071-3400; 17224-730; 72789-117; 17224-760; 62135-489; 0527-1477; 63187-947; 0527-1475; 71335-0049; 43063-532; 50090-0120; 50090-0327; 63629-8215; 38779-0926; 10702-044; 71335-0175
UNII 19V2PL39NG
Synonyms Diethylpropion | Amfepramon | Amfepramone | Phepranon | 2-Diethylaminopropiophenone | Anorex | Lipomin | Regenon | Dietil-retard | Dietil retard | Dietilretard | Regibon | Tenuate | Delgamer | Maruate | Modératan | Neobes | Nobesine | Propion | Préfamone | Tepanil | Diethylpropion Hydrochloride | Hydrochloride, Diethylpropion | Ifa Norex | Norex, Ifa
Chemical Information
Molecular Formula C13H20ClNO
CAS Registry Number 134-80-5
SMILES CCN(CC)C(C)C(=O)C1=CC=CC=C1.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Agranulocytosis01.02.03.001---
Alopecia23.02.02.001--
Anxiety19.06.02.002--
Arrhythmia02.03.02.001---
Blood pressure increased13.14.03.005---
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Constipation07.02.02.001--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyskinesia17.01.02.006--
Dysphoria19.04.02.004---
Dyspnoea02.11.05.003; 22.02.01.004--
Dysuria20.02.02.002--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002---
Electrocardiogram abnormal13.14.05.001---
Erythema23.03.06.001---
Euphoric mood19.04.02.006--
Feeling jittery08.01.09.016---
Gastrointestinal disorder07.11.01.001---
Gynaecomastia05.05.02.003; 21.05.04.003--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Insomnia17.15.03.002; 19.02.01.002--
Leukopenia01.02.02.001---
Malaise08.01.01.003--
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