Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Coma
ADR ID BADD_A00985
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.09      Coma states
17.02.09.001      Coma
Description A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION. | Feigned coma or psychogenic coma. These patients appear comatose (i.e., unresponsive, unarousable, or both) but have no structural lesion, metabolic or toxic disorder. [MeSH]
MedDRA Code 10010071
MeSH ID D003128
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Coma | Coma (non-diabetic) | Coma and stupor | Coma NEC | Coma NOS | Coma (NOS) | Comatose | Comas | Pseudocoma | Pseudocomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01954Rivaroxaban--
BADD_D01955Rivastigmine0.001084%
BADD_D01956Rivastigmine tartrate--
BADD_D01959Rocuronium0.000085%
BADD_D01966Ropinirole--
BADD_D01968Ropivacaine hydrochloride--
BADD_D01969Ropivacaine hydrochloride monohydrate--
BADD_D01971Rosuvastatin0.000068%
BADD_D01997Secobarbital--
BADD_D02002Selegiline--
BADD_D02010Sertraline0.000248%
BADD_D02011Sertraline hydrochloride--
BADD_D02015Sevoflurane0.000714%
BADD_D02032Sodium acetate--
BADD_D02045Sodium nitrite--
BADD_D02047Sodium oxybate0.008852%
BADD_D02058Sorafenib0.000783%
BADD_D02060Sotalol0.000984%
BADD_D02082Sufentanil0.000357%
BADD_D02084Sugammadex0.001239%
BADD_D02097Sulindac--
BADD_D02103Suvorexant0.000261%
BADD_D02104Tacrine hydrochloride--
BADD_D02105Tacrolimus--
BADD_D02115Tapentadol0.001911%
BADD_D02148Temazepam--
BADD_D02175Tetrabenazine0.001346%
BADD_D02195Theophylline--
BADD_D02203Thiotepa0.000168%
BADD_D02210Tiagabine--
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ADReCS-Target
ADR Term Drug Name Target