Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Ropivacaine hydrochloride
Drug ID BADD_D01968
Description Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by AstraZeneca under the trade name Naropin. It is present as a racemic mixture of the enantiomers containing equal proportions of the “S” and “R” forms. The marketed form contains the single S-enantiomer as the active ingredient.
Indications and Usage Used in obstetric anesthesia and regional anesthesia for surgery.
Marketing Status approved
ATC Code N01BB09
DrugBank ID DB00296
KEGG ID D04048
MeSH ID D000077212
PubChem ID 175804
TTD Drug ID D09RHQ
NDC Product Code 25021-671; 55150-197; 68083-263; 0409-9300; 70121-1734; 51552-1590; 0143-9263; 52584-286; 55150-201; 63323-286; 63323-288; 70069-063; 70121-1733; 70121-1735; 61876-0071; 43066-027; 0404-9924; 70069-067; 55150-196; 63323-285; 0409-9302; 70069-061; 70121-1732; 72572-707; 55150-200; 65145-107; 65145-108; 0409-9301; 70069-062; 76339-124; 17478-082; 43066-023; 0143-9266; 48954-722; 25021-652; 68083-262; 46014-1058; 49452-6303; 65372-1159; 17478-081; 0409-9303; 70069-064; 49386-025; 43066-015; 43066-019; 55150-198; 63323-287; 65145-109; 65145-110; 70069-065; 70069-066; 0143-9264; 0143-9265; 55150-195; 55150-199
UNII V910P86109
Synonyms Ropivacaine | 1-Propyl-2',6'-pipecoloxylidide | 1 Propyl 2',6' pipecoloxylidide | Naropin | Ropivacaine Monohydrochloride | Ropivacaine Hydrochloride | AL 381 | AL-381 | AL381 | Naropeine | LEA 103 | LEA-103 | LEA103 | Ropivacaine Monohydrochloride, (S)-isomer
Chemical Information
Molecular Formula C17H27ClN2O
CAS Registry Number 98717-15-8
SMILES CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abnormal labour18.07.02.001---
Accident12.01.08.001---
Acidosis14.01.03.002--
Acoustic stimulation tests abnormal13.07.08.001---
Agitation17.02.05.012; 19.06.02.001--
Alanine aminotransferase increased13.03.04.005--
Albuminuria20.02.01.001---
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anterior spinal artery syndrome17.10.01.008; 24.04.06.015---
Anxiety19.06.02.002--
Apgar score low13.15.01.012---
Apnoea22.02.01.001--
Application site reaction08.02.01.006; 12.07.01.006---
Arachnoiditis12.02.04.002; 17.06.01.001--
Arrhythmia02.03.02.001---
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001---
Atelectasis22.01.02.001--
Atrial fibrillation02.03.03.002--
Atrioventricular block02.03.01.002---
Back pain15.03.04.005--
Blood creatine phosphokinase increased13.04.01.001--
Blood urea decreased13.13.01.017---
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