Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ropivacaine hydrochloride monohydrate
Drug ID BADD_D01969
Description Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by AstraZeneca under the trade name Naropin. It is present as a racemic mixture of the enantiomers containing equal proportions of the “S” and “R” forms. The marketed form contains the single S-enantiomer as the active ingredient.
Indications and Usage Used in obstetric anesthesia and regional anesthesia for surgery.
Marketing Status Prescription; Discontinued
ATC Code N01BB09
DrugBank ID DB00296
KEGG ID D08490
MeSH ID D000077212
PubChem ID 6918111
TTD Drug ID D09RHQ
NDC Product Code 66583-0610; 72375-0004
Synonyms Ropivacaine | 1-Propyl-2',6'-pipecoloxylidide | 1 Propyl 2',6' pipecoloxylidide | Naropin | Ropivacaine Monohydrochloride | Ropivacaine Hydrochloride | AL 381 | AL-381 | AL381 | Naropeine | LEA 103 | LEA-103 | LEA103 | Ropivacaine Monohydrochloride, (S)-isomer
Chemical Information
Molecular Formula C17H29ClN2O2
CAS Registry Number 132112-35-7
SMILES CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Accident12.01.08.001--Not Available
Acoustic stimulation tests abnormal13.07.01.004--Not Available
Agitation17.02.05.012; 19.06.02.001--
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Apgar score low13.15.01.012--Not Available
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Back pain15.03.04.005--
Bradycardia02.03.02.002--Not Available
Bradycardia foetal02.03.02.018; 18.03.02.006--Not Available
Breast feeding26.05.01.001--Not Available
Bronchospasm10.01.03.012; 22.03.01.004--
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Chills08.01.09.001; 15.05.03.016--
Coma17.02.09.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Cough22.02.03.001--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dyskinesia17.01.02.006--
Dyspnoea02.01.03.002; 22.02.01.004--
Electrocardiogram abnormal13.14.05.001--Not Available
Electrocardiogram ST segment abnormal13.14.05.017--Not Available
Extrasystoles02.03.02.003--Not Available
Eyelid ptosis06.05.01.002; 17.17.02.004--Not Available
Failed trial of labour18.07.03.002--Not Available
Fever neonatal08.05.02.007; 18.04.01.009--Not Available
Foetal distress syndrome18.03.02.003--Not Available
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