Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Systemic lupus erythematosus
ADR ID BADD_A04225
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.03      Lupus erythematosus and associated conditions
10.04.03.004      Systemic lupus erythematosus
15      Musculoskeletal and connective tissue disorders
15.06      Connective tissue disorders (excl congenital)
15.06.02      Lupus erythematosus (incl subtypes)
15.06.02.003      Systemic lupus erythematosus
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.02      Connective tissue disorders
23.03.02.006      Systemic lupus erythematosus
Description A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. [MeSH]
MedDRA Code 10042945
MeSH ID D008180
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Disseminated lupus erythematosus | LE reaction systemic | LE syndrome | LE syndrome aggravated | LE systemic | LE type reaction | Lupus erythematosis (NOS) | Lupus erythematosis disseminated | Lupus erythematosus | Lupus erythematosus systemic | Lupus syndrome | SLE | SLE syndrome aggravated | SLE-like symptom | SLE-like symptoms | Syndrome disseminated lupus erythematosis | Syndrome lupus | Systemic lupus erythematosis | Systemic lupus erythematosus | Systemic lupus erythematosus synd | Systemic lupus erythematosus syndrome aggravated | SLE flare | Rowell's syndrome | Systemic lupus erythematosus reactivation | SLE reactivation | Lupus Erythematosus, Systemic | Systemic Lupus Erythematosus | Lupus Erythematosus Disseminatus | Libman-Sacks Disease | Disease, Libman-Sacks | Libman Sacks Disease
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000064r,6r-dorzolamide--
BADD_D00019Acebutolol--
BADD_D00020Acebutolol hydrochloride--
BADD_D00023Acetaminophen--
BADD_D00029Acetyl sulfisoxazole--
BADD_D00056Albuterol0.000006%
BADD_D00066Alendronic acid0.000066%
BADD_D00100Ambrisentan0.002082%
BADD_D00129Amoxicillin0.000018%
BADD_D00178Atenolol--
BADD_D00195Azathioprine0.001723%
BADD_D00263Betaxolol--
BADD_D00271Bicalutamide0.002812%
BADD_D00277Bisoprolol0.000785%
BADD_D00285Bosentan0.002299%
BADD_D00306Budesonide--
BADD_D00312Bupropion0.000068%
BADD_D00356Carbamazepine0.000651%
BADD_D00410Celecoxib0.000075%
BADD_D00412Cephalexin0.000017%
BADD_D00415Cerivastatin--
BADD_D00417Cetirizine--
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00440Chloroquine0.000142%
BADD_D00445Chlorpromazine--
BADD_D00446Chlorpromazine hydrochloride--
BADD_D00448Chlorthalidone0.000201%
BADD_D00465Cilazapril monohydrate--
BADD_D00499Clomipramine--
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ADReCS-Target
ADR Term Drug Name Target