Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Alendronic acid
Drug ID BADD_D00066
Description Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.
Marketing Status Prescription; Discontinued
ATC Code M05BA04
DrugBank ID DB00630
KEGG ID D07119
MeSH ID D019386
PubChem ID 2088
TTD Drug ID D09KLR
NDC Product Code Not Available
Synonyms Alendronate | 4-Amino-1-Hydroxybutylidene 1,1-Biphosphonate | Aminohydroxybutane Bisphosphonate | MK-217 | MK 217 | MK217 | Alendronate Monosodium Salt, Trihydrate | Alendronate Sodium | Fosamax
Chemical Information
Molecular Formula C4H13NO7P2
CAS Registry Number 66376-36-1
SMILES C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal adhesions07.07.03.001; 12.02.03.0060.000303%Not Available
Abdominal discomfort07.01.06.0010.003940%Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.0020.005153%
Abdominal pain lower07.01.05.0100.000909%Not Available
Abdominal pain upper07.01.05.0030.003738%
Abscess11.01.08.0010.002425%Not Available
Acne23.02.01.001--Not Available
Acrochordon16.26.01.005; 23.10.01.0050.000606%Not Available
Actinic keratosis23.01.06.0010.001920%Not Available
Acute myocardial infarction02.02.02.001; 24.04.04.001--Not Available
Acute prerenal failure20.01.03.001; 24.06.02.0030.000202%Not Available
Acute respiratory failure14.01.04.004; 22.02.06.0010.000158%Not Available
Acute sinusitis11.01.13.012; 22.07.03.0130.001920%Not Available
Adrenal disorder05.01.03.0010.000303%Not Available
Adrenal insufficiency05.01.02.001; 14.11.01.0040.000404%
Agitation17.02.05.012; 19.06.02.001--
Alanine aminotransferase increased13.03.01.003--
Alcohol abuse19.07.02.0070.000808%Not Available
Alopecia23.02.02.001--
Altered state of consciousness17.02.04.001; 19.07.01.003--Not Available
Amaurosis fugax06.02.02.005; 17.08.04.002; 24.04.06.0060.000202%Not Available
Amenorrhoea05.05.01.002; 21.01.02.001--
Amnesia17.03.02.001; 19.20.01.0010.002627%
Anaemia01.03.02.0010.015155%
Anaemia macrocytic01.03.02.002; 14.12.01.0020.000505%Not Available
Anal fistula07.11.05.0020.000202%
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anastomotic ulcer07.04.04.003; 12.02.03.001--
Angina pectoris02.02.02.002; 24.04.04.0020.001617%
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