Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Rhabdomyolysis
ADR ID BADD_A03877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.05      Myopathies
15.05.05.002      Rhabdomyolysis
Description A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. [CTCAE] Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. [MeSH]
MedDRA Code 10039020
MeSH ID D012206
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Muscle dissolution | Rhabdomyolysis | Rhabdomyolyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01450Metyrapone0.000099%
BADD_D01466Milnacipran hydrochloride--
BADD_D01476Mirtazapine0.001360%
BADD_D01498Morphine0.001671%
BADD_D01501Moxifloxacin--
BADD_D01508Mycophenolic acid0.000951%
BADD_D01546Nefazodone--
BADD_D01547Nefazodone hydrochloride--
BADD_D01549Nelarabine0.000112%
BADD_D01550Nelfinavir mesylate--
BADD_D01557Nevirapine--
BADD_D01559Niacin0.000667%
BADD_D01563Nicotinate--
BADD_D01567Nilotinib0.001175%
BADD_D01598Ofloxacin0.000125%
BADD_D01599Olanzapine0.011577%
BADD_D01600Olanzapine pamoate--
BADD_D01602Olmesartan--
BADD_D01603Olmesartan medoxomil--
BADD_D01629Osimertinib0.000728%
BADD_D01633Oxaliplatin--
BADD_D01636Oxazepam0.002280%
BADD_D01637Oxcarbazepine0.001056%
BADD_D01656Paliperidone0.024587%
BADD_D01668Pantoprazole0.000090%
BADD_D01669Pantoprazole sodium--
BADD_D01679Paroxetine0.000064%
BADD_D01696Peginterferon alfa-2b--
BADD_D01710Penicillin g0.005989%
BADD_D01711Penicillin g benzathine--
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ADReCS-Target
ADR Term Drug Name Target