Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Nelfinavir mesylate
Drug ID BADD_D01550
Description Nelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
Indications and Usage Used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
Marketing Status approved
ATC Code J05AE04
DrugBank ID DB00220
KEGG ID D00899
MeSH ID D019888
PubChem ID 64142
TTD Drug ID Not Available
NDC Product Code 63010-010; 63010-027
UNII 98D603VP8V
Synonyms Nelfinavir | Viracept | AG 1343 | AG1343 | AG-1343 | Nelfinavir Mesylate | Mesylate, Nelfinavir | Nelfinavir Monomethane Sulfonate | Monomethane Sulfonate, Nelfinavir | Sulfonate, Nelfinavir Monomethane
Chemical Information
Molecular Formula C33H49N3O7S2
CAS Registry Number 159989-65-8
SMILES CC1=C(C=CC=C1O)C(=O)NC(CSC2=CC=CC=C2)C(CN3CC4CCCCC4CC3C(=O)NC(C)(C)C)O.CS(=O)(=O )O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Agitation17.02.05.012; 19.06.02.001--
Alanine aminotransferase13.03.04.002---
Alanine aminotransferase increased13.03.04.005--
Amylase increased13.05.01.009--
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Aspartate aminotransferase13.03.04.008---
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001---
Back pain15.03.04.005--
Blood cholesterol increased13.12.01.002--
Blood creatine phosphokinase13.04.01.009---
Blood creatine phosphokinase increased13.04.01.001--
Blood lactate dehydrogenase increased13.04.02.002--
Blood triglycerides increased13.12.03.001---
Blood uric acid increased13.02.04.001---
Body temperature increased13.15.01.001---
Breast enlargement21.05.04.001---
Bronchospasm10.01.03.012; 22.03.01.004--
Completed suicide08.04.01.010; 19.12.01.001---
Dehydration14.05.05.001--
Depression19.15.01.001--
Dermatitis23.03.04.002---
Dermatitis bullous23.03.01.002--
Diabetes mellitus05.06.01.001; 14.06.01.001---
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