Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status approved
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 72789-246; 68084-918; 70518-3218; 70748-218; 16729-189; 72789-247; 60505-2965; 67877-427; 70436-172; 0904-6785; 0078-0386; 16729-261; 70377-039; 0904-6786; 20076-0405; 50268-559; 60429-016; 60505-2966; 68084-907; 68254-5002; 50090-6492; 0378-4201; 52076-6215; 57885-0009; 60429-017; 67877-426; 70518-3255; 24979-161; 0378-4202; 70436-173; 70748-217; 65727-011; 0078-0385; 24979-160; 68254-5001; 70377-040; 51187-0004
UNII HU9DX48N0T
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.012269%-
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.0020.006372%
Abdominal pain lower07.01.05.010---
Abdominal pain upper07.01.05.003--
Abdominal tenderness07.01.05.004---
Abnormal dreams17.15.02.001; 19.02.03.001---
Abscess11.01.08.001---
Acidosis14.01.03.002--
Acne23.02.01.001---
Acquired immunodeficiency syndrome10.03.03.001; 11.05.17.007---
Agitation17.02.05.012; 19.06.02.001--
Agranulocytosis01.02.03.0010.004755%-
Akathisia17.01.02.002; 19.06.02.006--
Alanine aminotransferase increased13.03.04.005--
Albuminuria20.02.01.001---
Alkalosis14.01.02.001--
Alopecia23.02.02.001--
Amblyopia06.02.01.001---
Amnesia17.03.02.001; 19.20.01.0010.002092%
Anaemia01.03.02.0010.005231%
Anaphylactic reaction10.01.07.001; 24.06.03.0060.001427%
Anaphylactic shock10.01.07.002; 24.06.02.0040.000951%-
Angina pectoris02.02.02.002; 24.04.04.0020.000951%
Anhidrosis23.02.03.001---
Anorectal disorder07.03.01.001---
Anxiety19.06.02.002--
Apathy19.04.04.002---
Aphthous ulcer07.05.06.0020.001427%-
Aplasia pure red cell01.03.03.001; 10.02.01.003---
The 1th Page    1 2 3 4 5    Next   Last    Total 17 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene