Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Rhabdomyolysis
ADR ID BADD_A03877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.05      Myopathies
15.05.05.002      Rhabdomyolysis
Description A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. [CTCAE] Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. [MeSH]
MedDRA Code 10039020
MeSH ID D012206
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Muscle dissolution | Rhabdomyolysis | Rhabdomyolyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00964Foscarnet sodium--
BADD_D00979Furosemide0.000333%
BADD_D00980Fusidic acid--
BADD_D00981Gabapentin0.000199%
BADD_D00982Gabapentin enacarbil-
BADD_D01003Ganciclovir--
BADD_D01004Ganciclovir sodium--
BADD_D01012Gemfibrozil0.001127%
BADD_D01023Glimepiride0.000170%
BADD_D01083Hydrochlorothiazide0.000042%
BADD_D01103Hydroxychloroquine0.003719%
BADD_D01111Hydroxyzine0.000056%
BADD_D01133Ifosfamide--
BADD_D01136Imatinib--
BADD_D01137Imatinib mesylate--
BADD_D01142Imiquimod0.000439%
BADD_D01149Indapamide0.001319%
BADD_D01150Indinavir--
BADD_D01167Interferon alfa-2b--
BADD_D01168Interferon alfacon-1--
BADD_D01178Iodixanol0.010670%
BADD_D01181Iopamidol0.007113%
BADD_D01194Irbesartan0.000568%
BADD_D01204Isoniazid0.044476%
BADD_D01213Isotretinoin--
BADD_D01217Itraconazole0.016034%
BADD_D01220Ivacaftor-
BADD_D01230Ketoconazole0.000244%
BADD_D01231Ketoprofen0.002240%
BADD_D01238Lacosamide0.006582%
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ADReCS-Target
ADR Term Drug Name Target