Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ganciclovir sodium
Drug ID BADD_D01004
Description An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Indications and Usage For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised patients.
Marketing Status approved; investigational
ATC Code S01AD09; J05AB06
DrugBank ID DB01004
KEGG ID D04301
MeSH ID D015774
PubChem ID 23700083
TTD Drug ID D05ARP
NDC Product Code 46014-1054; 70436-089; 25021-185; 63323-315; 0143-9299; 51817-171; 0004-6941
UNII 02L083W284
Synonyms Ganciclovir | Gancyclovir | BW-759 | Ganciclovir Sodium | Ganciclovir, Monosodium Salt | RS-21592 | BIOLF-62 | Cytovene
Chemical Information
Molecular Formula C9H12N5NaO4
CAS Registry Number 84245-13-6
SMILES C1=NC2=C(N1COC(CO)CO)N=C(N=C2[O-])N.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abnormal dreams17.15.02.001; 19.02.03.001---
Acidosis14.01.03.002--
Agitation17.02.05.012; 19.06.02.001--
Agranulocytosis01.02.03.001---
Alanine aminotransferase increased13.03.04.005--
Alopecia23.02.02.001--
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anosmia17.04.04.001; 22.04.03.006--
Anxiety19.06.02.002--
Aphasia17.02.03.001; 19.21.01.001--
Arrhythmia02.03.02.001---
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001---
Back pain15.03.04.005--
Blood creatinine13.13.01.020---
Blood triglycerides increased13.12.03.001---
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.001--
Cataract06.06.01.001--
Catheter site related reaction08.02.02.001; 12.07.02.001---
Cellulitis11.02.01.001; 23.11.02.004---
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Chills08.01.09.001; 15.05.03.016--
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