Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Indinavir
Drug ID BADD_D01150
Description A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Indications and Usage Indinavir is an antiretroviral drug for the treatment of HIV infection.
Marketing Status Prescription; Discontinued
ATC Code J05AE02
DrugBank ID DB00224
KEGG ID C07051
MeSH ID D019469
PubChem ID 5362440
TTD Drug ID D0V7CF
NDC Product Code Not Available
Synonyms Indinavir | MK-639 | MK 639 | MK639 | L-735 524 | L 735 524 | L735 524 | L-735,524 | L 735,524 | L735,524 | Crixivan | Indinavir Sulfate | Sulfate, Indinavir | Indinavir, Sulfate (1:1)
Chemical Information
Molecular Formula C36H47N5O4
CAS Registry Number 150378-17-9
SMILES CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=CC= C5
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Accommodation disorder06.02.04.001--Not Available
Acquired immunodeficiency syndrome10.03.03.001; 11.05.17.007--Not Available
Agitation17.02.05.012; 19.06.02.001--
Alanine aminotransferase increased13.03.01.003--
Alopecia23.02.02.001--
Amylase increased13.05.01.009--
Anaemia01.03.02.001--
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema10.01.05.009; 23.04.01.001--Not Available
Anxiety19.06.02.002--
Aphthous ulcer07.05.06.002--Not Available
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Bacteraemia11.01.11.001--
Basedow's disease05.02.02.003; 06.09.04.003; 10.04.08.004--Not Available
Blood bilirubin unconjugated increased13.03.01.024--Not Available
Blood cholesterol increased13.12.01.002--
Blood creatinine increased13.13.01.004--
Blood glucose increased13.02.02.002--Not Available
Blood triglycerides increased13.12.03.001--Not Available
Body temperature increased13.15.01.001--Not Available
Breath odour07.01.06.002--Not Available
Bruxism07.01.06.008; 19.11.03.001--Not Available
Calculus urinary20.04.02.001--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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