Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00157Aprepitant0.000162%
BADD_D00161Argatroban0.000123%
BADD_D00165Aripiprazole--
BADD_D00169Arsenic trioxide0.000112%
BADD_D00171Ascorbic acid0.000496%
BADD_D00189Atropine--
BADD_D00190Atropine sulfate--
BADD_D00194Azacitidine0.003134%
BADD_D00195Azathioprine0.002506%
BADD_D00209Baclofen0.002960%
BADD_D00214Basiliximab--
BADD_D00230Bendamustine0.000895%
BADD_D00255Beractant--
BADD_D00257Beta-d-glucose--
BADD_D00263Betaxolol--
BADD_D00264Betaxolol hydrochloride--
BADD_D00271Bicalutamide0.007733%
BADD_D00277Bisoprolol0.001570%
BADD_D00282Blinatumomab--
BADD_D00283Boceprevir--
BADD_D00284Bortezomib--
BADD_D00285Bosentan0.010049%
BADD_D00286Bosutinib--
BADD_D00287Bosutinib monohydrate--
BADD_D00294Brimonidine0.000211%
BADD_D00297Brivaracetam0.000249%
BADD_D00306Budesonide0.000465%
BADD_D00308Bupivacaine0.000536%
BADD_D00310Buprenorphine--
BADD_D00318Busulfan0.000392%
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