Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Atropine
Drug ID BADD_D00189
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status Prescription; Discontinued
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D00113
MeSH ID D001285
PubChem ID 174174
TTD Drug ID D0RG3O
NDC Product Code 69205-034; 60592-049; 11704-105; 63827-1015; 13371-488; 12714-034; 11704-106; 64181-0048; 11704-107; 11704-101; 11704-104
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augen？l | Augen？l, Atropin
Chemical Information
Molecular Formula C17H23NO3
CAS Registry Number 51-55-8
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Accommodation disorder06.02.04.001--Not Available
Agitation17.02.05.012; 19.06.02.0010.002403%
Amnesia17.03.02.001; 19.20.01.001--
Anaphylactic shock10.01.07.002; 24.06.02.0040.000687%Not Available
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema10.01.05.009; 23.04.01.001--Not Available
Angle closure glaucoma06.03.01.001--Not Available
Anhidrosis23.02.03.001--Not Available
Anticholinergic syndrome17.05.01.0010.002747%Not Available
Anxiety19.06.02.002--
Arrhythmia supraventricular02.03.03.001--Not Available
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Atrial fibrillation02.03.03.002--
Blepharitis06.04.04.001; 23.03.04.012--Not Available
Blindness06.02.02.001; 17.17.01.003--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.0020.000687%Not Available
Cardiac arrest02.03.04.0010.000179%
Cerebellar syndrome17.02.02.002--Not Available
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Choroidal detachment06.09.01.003; 12.01.04.0060.000687%Not Available
Clonus17.02.05.002--Not Available
Coma17.02.09.001--Not Available
Confusional state17.02.03.005; 19.13.01.0010.001717%
Conjunctivitis06.04.01.002; 11.01.06.012--
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ADReCS-Target
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