Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Betaxolol hydrochloride
Drug ID BADD_D00264
Description A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Indications and Usage For the management of hypertension.
Marketing Status approved; investigational
ATC Code S01ED02; C07AB05
DrugBank ID DB00195
KEGG ID D00598
MeSH ID D015784
PubChem ID 107952
TTD Drug ID D03ROX
NDC Product Code 14445-002; 17337-0503; 10702-014; 0078-0729; 59349-0005; 0065-0246; 61314-245; 17478-705; 10702-013
UNII 6X97D2XT0O
Synonyms Betaxolol | Betaxolol Hydrochloride | Hydrochloride, Betaxolol | Kerlone | Oxodal | Kerlon | SL-75212 | SL 75212 | SL75212 | ALO-1401-02 | ALO 1401 02 | ALO140102 | Betoptic | Betoptima | Betaxolol Alcon | Alcon, Betaxolol
Chemical Information
Molecular Formula C18H30ClNO3
CAS Registry Number 63659-19-8
SMILES CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Asthma10.01.03.010; 22.03.01.002---
Atrioventricular block02.03.01.002---
Bradycardia02.03.02.002---
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac failure congestive02.05.01.002---
Depression19.15.01.001--
Discomfort08.01.08.003---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyspnoea02.11.05.003; 22.02.01.004--
Erythema23.03.06.001---
Glossitis07.14.01.001---
Headache17.14.01.001--
Hypoaesthesia eye06.01.01.007; 17.02.06.019---
Insomnia17.15.03.002; 19.02.01.002--
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004--
Myasthenia gravis10.04.05.001; 15.05.08.001; 17.05.04.001--
Oedema08.01.07.006; 14.05.06.010---
Photophobia06.01.01.004; 17.17.02.006--
Pruritus23.03.12.001--
Respiratory failure14.01.04.003; 22.02.06.002--
Toxic epidermal necrolysis10.01.01.006; 11.07.01.006; 12.03.01.015; 23.03.01.008--
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
Vital dye staining cornea present13.07.04.010---
Increased bronchial secretion22.12.01.002---
Anisocoria06.05.03.013; 17.02.11.009---
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