Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000064r,6r-dorzolamide--
BADD_D00008Abacavir--
BADD_D00009Abacavir succinate--
BADD_D00023Acetaminophen0.000071%
BADD_D00033Acetylsalicylic acid--
BADD_D00036Acitretin0.001250%
BADD_D00045Adenosine--
BADD_D00047Afatinib0.002015%
BADD_D00049Agalsidase beta--
BADD_D00056Albuterol0.000065%
BADD_D00062Aldesleukin--
BADD_D00066Alendronic acid0.000550%
BADD_D00071Alglucosidase alfa--
BADD_D00073Aliskiren0.000609%
BADD_D00076Allopurinol--
BADD_D00085Alprazolam0.000311%
BADD_D00097Amantadine0.000393%
BADD_D00100Ambrisentan0.011156%
BADD_D00103Amikacin0.000169%
BADD_D00106Aminocaproic acid0.000229%
BADD_D00110Aminolevulinic acid--
BADD_D00115Amiodarone0.008915%
BADD_D00116Amiodarone hydrochloride--
BADD_D00118Amitriptyline0.000169%
BADD_D00121Amlodipine0.000025%
BADD_D00126Amobarbital--
BADD_D00130Amphetamine0.000201%
BADD_D00132Amphotericin b0.000282%
BADD_D00142Anastrozole0.000556%
BADD_D00151Apixaban--
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