Drug Name |
Abacavir |
Drug ID |
BADD_D00008 |
Description |
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir. |
Indications and Usage |
For the treatment of HIV-1 infection, in combination with other antiretroviral agents. |
Marketing Status |
approved; investigational |
ATC Code |
J05AF06 |
DrugBank ID |
DB01048
|
KEGG ID |
D07057
|
MeSH ID |
C106538
|
PubChem ID |
441300
|
TTD Drug ID |
D0A4IJ
|
NDC Product Code |
55111-920; 72865-167; 50268-049; 31722-562; 70518-1274; 65862-073; 31722-557; 68084-021; 0904-6874; 64380-717; 69097-514 |
UNII |
WR2TIP26VS
|
Synonyms |
abacavir | 1592U89 | abacavir sulfate | Ziagen | (1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol | abacavir succinate |