Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Optic atrophy
ADR ID BADD_A03173
ADR Hierarchy
06      Eye disorders
06.09      Ocular structural change, deposit and degeneration NEC
06.09.02      Optic disc abnormalities NEC
06.09.02.001      Optic atrophy
Description Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition. [MeSH]
MedDRA Code 10030910
MeSH ID D009896
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Atrophy optic | Atrophy optic nerve | Optic atrophy | Optic atrophy associated with retinal dystrophies | Optic atrophy, unspecified | Optic disc atrophy | Optic disc pallor excessive | Partial optic atrophy | Postinflammatory optic atrophy | Primary optic atrophy | Temporal pallor (optic disc) | Post inflammatory optic atrophy | Optic nerve pallor | Optic Atrophy | Atrophy, Optic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00033Acetylsalicylic acid0.000022%
BADD_D00115Amiodarone0.000135%
BADD_D00364Carboplatin0.000280%
BADD_D00407Cefuroxime0.001288%
BADD_D00429Chlorambucil--
BADD_D00440Chloroquine0.000213%
BADD_D00551Cyclosporine0.000111%
BADD_D00554Cyproterone--
BADD_D00555Cyproterone acetate--
BADD_D00623Dexamethasone0.000291%
BADD_D00749Efavirenz0.003670%
BADD_D00898Finasteride0.000045%
BADD_D00981Gabapentin--
BADD_D01103Hydroxychloroquine--
BADD_D01243Lamotrigine0.000055%
BADD_D01265Levetiracetam0.000079%
BADD_D01303Lithium carbonate--
BADD_D01304Lithium cation--
BADD_D01305Lithium hydroxide--
BADD_D01313Lomustine--
BADD_D01376Melphalan0.000168%
BADD_D01433Methylprednisolone0.000064%
BADD_D01470Minocycline0.000295%
BADD_D01614Omeprazole--
BADD_D01615Omeprazole magnesium--
BADD_D01834Prednisone0.000009%
BADD_D01835Pregabalin0.000052%
BADD_D01895Quinine0.004036%
BADD_D01926Reserpine--
BADD_D02105Tacrolimus0.001188%
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