Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Nephrotic syndrome
ADR ID BADD_A03027
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.002      Nephrotic syndrome
Description A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. [CTCAE] Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. [MeSH]
MedDRA Code 10029164
MeSH ID D009401; D009404
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Nephrosis | Nephrosis osmotic | Nephrotic syndrome | Nephrotic syndrome in diseases classified elsewhere | Nephrotic syndrome with lesion of membranoproliferative glomerulonephritis | Nephrotic syndrome with lesion of membranous glomerulonephritis | Nephrotic syndrome with lesion of minimal change glomerulonephritis | Nephrotic syndrome with lesion of proliferative glomerulonephritis | Nephrotic syndrome with other pathological lesion in kidney | Nephrotic syndrome with other specified pathological lesion in kidney | Nephrotic syndrome with unspecified pathological lesion in kidney | Syndrome nephrotic | Nephrotic syndrome worsened | Steroid-resistant nephrotic syndrome | Nephroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00556Cysteamine0.000315%
BADD_D00562Cytomegalovirus immune globulin (human)--
BADD_D00578Dapagliflozin0.000219%
BADD_D00580Dapsone0.000367%
BADD_D00589Dasatinib0.001343%
BADD_D00594Deferasirox0.002478%
BADD_D00646Diatrizoate sodium--
BADD_D00647Diatrizoic acid--
BADD_D00649Diazoxide--
BADD_D00653Diclofenac0.000115%
BADD_D00666Diflunisal--
BADD_D00723Doxorubicin0.000112%
BADD_D00745Edetic acid--
BADD_D00765Empagliflozin0.000182%
BADD_D00856Etoricoxib--
BADD_D00858Everolimus0.001452%
BADD_D00871Felbamate--
BADD_D00877Fenoprofen--
BADD_D00878Fenoprofen calcium--
BADD_D00979Furosemide0.000028%
BADD_D00981Gabapentin--
BADD_D01009Gemcitabine0.000280%
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01042Griseofulvin--
BADD_D01119Ibrutinib0.000560%
BADD_D01120Ibuprofen0.000009%
BADD_D01130Idelalisib0.000112%
BADD_D01136Imatinib0.000224%
BADD_D01144Immunoglobulin (human)--
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