Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Diatrizoate sodium
Drug ID BADD_D00646
Description A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Indications and Usage Used, alone or in combination, for a wide variety of diagnostic imaging methods, including angiography, urography, cholangiography, computed tomography, hysterosalpingography, and retrograde pyelography. It can be used for imaging the gastrointestinal tract in patients allergic to barium.
Marketing Status approved; vet_approved
ATC Code V08AA01
DrugBank ID DB00271
KEGG ID D01013
MeSH ID D003973
PubChem ID 23672589
TTD Drug ID D0T9DT
NDC Product Code 66577-032; 76055-0014; 65392-1701; 69037-0052
UNII V5403H8VG7
Synonyms Diatrizoate | Benzoic acid, 3,5-bis(acetylamino)-2,4,6-triiodo- | Hypaque | Diatrizoic Acid | Urothrast | Urotrast | Urogranoic Acid | Sodium Diatrizoate | Diatrizoate, Sodium | Diatrizoate Sodium | Sodium-Magnesium Diatrizoate | Diatrizoate, Sodium-Magnesium | Amidotrezoate | Amidotrizoate | Hypaque 50
Chemical Information
Molecular Formula C11H8I3N2NaO4
CAS Registry Number 737-31-5
SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)[O-])I)NC(=O)C)I.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Asthma10.01.03.010; 22.03.01.002---
Azotaemia20.01.01.001---
Blood creatinine increased13.13.01.004--
Blood urea increased13.13.01.006---
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.001--
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Circulatory collapse24.06.02.001---
Coma17.02.09.001---
Conjunctival oedema06.04.01.001---
Conjunctivitis06.04.01.002; 11.01.06.012--
Cough22.02.03.001--
Death08.04.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspnoea02.11.05.003; 22.02.01.004--
Electrocardiogram abnormal13.14.05.001---
Extravasation08.01.03.008---
Eye irritation06.04.05.003---
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Infection11.01.08.002---
Injection site pain08.02.03.010; 12.07.03.011---
Lacrimation increased06.08.02.004--
Laryngeal oedema10.01.05.003; 22.04.02.001; 23.04.01.005--
Leukopenia01.02.02.001---
Malaria01.03.02.007; 11.06.04.001---
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