Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Muscle contractions involuntary
ADR ID BADD_A02877
ADR Hierarchy
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.03      Neuromuscular disorders NEC
17.05.03.001      Muscle contractions involuntary
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.008      Muscle contractions involuntary
Description Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294) [MeSH]
MedDRA Code 10028293
MeSH ID D005207
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Contraction skeletal muscle | Fasciculation | Fasciculation skeletal muscle | Fibrillation skeletal muscle | Muscle contractions involuntary | Muscle fasciculation | Muscle fibrillation | Fasciculations | Fasciculation, Muscular | Fasciculations, Muscular | Muscular Fasciculation | Muscular Fasciculations | Fasciculation, Tongue | Fasciculations, Tongue | Tongue Fasciculation | Tongue Fasciculations | Fasciculation, Benign | Benign Fasciculation | Benign Fasciculations | Fasciculations, Benign | Fasciculation, Skeletal Muscle | Fasciculations, Skeletal Muscle | Muscle Fasciculation, Skeletal | Muscle Fasciculations, Skeletal | Skeletal Muscle Fasciculation | Skeletal Muscle Fasciculations
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00013Abciximab--
BADD_D00085Alprazolam0.000029%
BADD_D00097Amantadine--
BADD_D00098Amantadine hydrochloride--
BADD_D00099Ambenonium chloride--
BADD_D00165Aripiprazole0.000277%
BADD_D00198Azelastine--
BADD_D00199Azelastine hydrochloride--
BADD_D00209Baclofen0.000432%
BADD_D00309Bupivacaine hydrochloride--
BADD_D00312Bupropion0.000018%
BADD_D00356Carbamazepine--
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00471Ciprofloxacin--
BADD_D00474Cisplatin--
BADD_D00475Citalopram0.000029%
BADD_D00476Citalopram hydrobromide--
BADD_D00501Clonazepam0.000030%
BADD_D00551Cyclosporine--
BADD_D00671Dihydroergotamine--
BADD_D00706Donepezil0.000535%
BADD_D00707Donepezil hydrochloride--
BADD_D00716Doxapram--
BADD_D00717Doxapram hydrochloride--
BADD_D00734Duloxetine0.000112%
BADD_D00747Edrophonium--
BADD_D00748Edrophonium chloride--
BADD_D00749Efavirenz--
BADD_D00773Entacapone--
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