Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Edrophonium
Drug ID BADD_D00747
Description A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Indications and Usage For the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment requirements in this disease. It may also be used for evaluating emergency treatment in myasthenic crises.
Marketing Status approved
ATC Code V04CX07
DrugBank ID DB01010
KEGG ID D00994
MeSH ID D004491
PubChem ID 3202
TTD Drug ID D0S5LH
NDC Product Code Not Available
UNII 70FP3JLY7N
Synonyms Edrophonium | Edroponium | Edrophonium Chloride | Chloride, Edrophonium | Tensilon | Edrophonium Bromide | Bromide, Edrophonium
Chemical Information
Molecular Formula C10H16NO+
CAS Registry Number 312-48-1
SMILES CC[N+](C)(C)C1=CC(=CC=C1)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Accommodation disorder06.02.04.001---
Arrhythmia02.03.02.001---
Asthenia08.01.01.001---
Bradycardia02.03.02.002---
Cardiac arrest02.03.04.001--
Diarrhoea07.02.01.001--
Diplopia06.02.06.002; 17.17.01.005---
Dysarthria17.02.08.001; 19.19.03.001--
Dysphagia07.01.06.003--
Dysphonia17.02.08.004; 19.19.03.002; 22.12.03.006--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypotension24.06.03.002--
Incontinence07.01.06.011; 17.05.01.006; 20.02.02.004---
Lacrimation increased06.08.02.004--
Laryngospasm22.04.02.002--
Muscle contractions involuntary15.05.03.008; 17.05.03.001---
Nausea07.01.07.001--
Osteoarthritis15.01.04.001---
Paralysis17.01.04.004---
Pollakiuria20.02.02.007--
Respiratory paralysis17.01.04.010; 22.02.06.003---
Seizure17.12.03.001--
Vomiting07.01.07.003--
Conjunctival hyperaemia06.04.01.004---
Abnormal behaviour19.01.01.001---
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