Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression. Off-label indications include: treatment of mild dementia-associated agitation in nonpsychotic patients, smoking cessation, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label].
Marketing Status Prescription
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 69097-823; 42806-020; 70518-0561; 43063-385; 43353-112; 70518-2228; 65162-054; 67046-102; 71610-092; 0456-4020; 50090-5170; 69097-824; 68788-7899; 70518-2617; 43063-063; 70934-539; 65162-052; 54458-980; 69097-822; 70518-2553; 0054-0062; 52427-691; 60429-174; 67046-106; 76282-629; 61919-390; 76282-628; 50090-5172; 54458-889; 70518-2601; 70518-2671; 54458-981; 0378-6233; 71335-0541; 60429-173; 71610-412; 63850-3616; 65162-053; 0378-6231; 0456-4010; 42806-021; 76282-206; 68071-3034; 67046-101; 70518-0449; 60429-175; 70934-397; 43353-208; 50090-5175; 63629-6761; 0456-4040; 61919-389; 76282-208; 71610-422; 80425-0093; 76282-207; 0378-6232; 43353-091; 42806-019
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.0010.000542%
Abdominal pain07.01.05.002--
Abdominal pain lower07.01.05.010--Not Available
Abdominal pain upper07.01.05.0030.001458%
Abnormal dreams17.15.02.001; 19.02.03.0010.000875%Not Available
Abnormal faeces07.01.03.0010.000125%Not Available
Abnormal weight gain14.03.02.0100.000054%Not Available
Abortion18.01.01.0010.000083%Not Available
Abortion missed18.01.01.0020.000250%Not Available
Abortion spontaneous18.01.04.001--Not Available
Abscess11.01.08.001--Not Available
Accommodation disorder06.02.04.0010.000292%Not Available
Acidosis14.01.03.0020.000333%
Acne23.02.01.001--Not Available
Acromegaly05.03.01.005; 14.11.01.029; 15.03.01.018; 24.08.04.0040.000083%Not Available
Acute hepatic failure09.01.03.0010.000054%Not Available
Acute psychosis19.03.01.0010.000083%Not Available
Acute respiratory distress syndrome22.01.03.0010.000196%
Acute respiratory failure14.01.04.004; 22.02.06.0010.000065%Not Available
Affective disorder19.04.04.0010.000250%Not Available
Ageusia07.14.03.003; 17.02.07.0010.000333%Not Available
Aggression19.05.01.0010.001750%Not Available
Agitation17.02.05.012; 19.06.02.0010.002666%
Agitation neonatal17.02.05.028; 18.04.04.002; 19.06.02.0070.000708%Not Available
Agranulocytosis01.02.03.001--Not Available
Akathisia17.01.02.002; 19.06.02.0060.000625%
Akinesia17.01.02.0030.000083%Not Available
Alanine aminotransferase increased13.03.01.003--
Alcohol abuse19.07.02.0070.000583%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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