Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Doxapram
Drug ID BADD_D00716
Description A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Indications and Usage For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.
Marketing Status approved; vet_approved
ATC Code R07AB01
DrugBank ID DB00561
KEGG ID D07873
MeSH ID D004315
PubChem ID 3156
TTD Drug ID D0M7BT
NDC Product Code Not Available
UNII 94F3830Q73
Synonyms Doxapram | Dopram | Doxapram Hydrochloride | Hydrochloride, Doxapram | Docatone
Chemical Information
Molecular Formula C24H30N2O2
CAS Registry Number 309-29-5
SMILES CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation17.02.05.012; 19.06.02.001--
Albuminuria20.02.01.001---
Anxiety19.06.02.002--
Arrhythmia02.03.02.001---
Blood pressure increased13.14.03.005---
Body temperature increased13.15.01.001---
Bronchospasm10.01.03.012; 22.03.01.004--
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.002---
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Clonus17.02.05.002---
Cough22.02.03.001--
Diarrhoea07.02.01.001--
Disorientation17.02.05.015; 19.13.01.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyskinesia17.01.02.006--
Dyspnoea02.11.05.003; 22.02.01.004--
Feeling hot08.01.09.009---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hiccups07.01.06.009; 22.12.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperkinesia17.01.02.008---
Hyperreflexia17.02.01.002---
Hyperventilation19.01.02.004; 22.02.01.006---
Hypoventilation22.02.01.007---
Hypoxia22.02.02.003--
Laryngospasm22.04.02.002--
Leukopenia01.02.02.001---
Muscle contractions involuntary15.05.03.008; 17.05.03.001---
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