Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Ketoacidosis
ADR ID BADD_A02446
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.01      Metabolic acidoses (excl diabetic acidoses)
14.01.01.008      Ketoacidosis
Description A condition characterized by an abnormally elevated concentration of KETONE BODIES in the blood (acetonemia) or urine (acetonuria). It is a sign of DIABETES COMPLICATION, starvation, alcoholism or a mitochondrial metabolic disturbance (e.g., MAPLE SYRUP URINE DISEASE). [MeSH]
MedDRA Code 10023379
MeSH ID D007662
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acetone breath | Breath odour ketones | Ketoacidosis | Breath odor ketones | Ketosis | Ketoacidoses | Metabolic Ketosis | Ketoses, Metabolic | Ketosis, Metabolic | Metabolic Ketoses | Metabolic Ketoacidosis | Ketoacidoses, Metabolic | Ketoacidosis, Metabolic | Metabolic Ketoacidoses | Acetonemia | Acetonemias | Ketonemia | Ketonemias | Ketoacidemia | Ketoacidemias | Ketonuria | Ketonurias | Ketoaciduria | Ketoacidurias | Acetonuria | Acetonurias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00018Acarbose0.001084%
BADD_D00165Aripiprazole0.000238%
BADD_D00169Arsenic trioxide--
BADD_D00277Bisoprolol0.000314%
BADD_D00344Canagliflozin0.008725%
BADD_D00511Clozapine--
BADD_D00578Dapagliflozin0.012065%
BADD_D00623Dexamethasone0.000218%
BADD_D00649Diazoxide--
BADD_D00765Empagliflozin0.027839%
BADD_D01159Insulin (human)--
BADD_D01160Insulin aspart--
BADD_D01330Lurasidone0.000328%
BADD_D01401Metformin0.000269%
BADD_D01512Nadolol0.002068%
BADD_D01599Olanzapine0.001473%
BADD_D01684Pasireotide0.000279%
BADD_D01717Pentamidine--
BADD_D01718Pentamidine isethionate--
BADD_D01867Propranolol0.000214%
BADD_D01888Quetiapine0.000055%
BADD_D01989Saquinavir mesylate--
BADD_D01992Saxagliptin0.000327%
BADD_D02010Sertraline0.000045%
BADD_D02029Sitagliptin0.000159%
BADD_D02254Tramadol0.000014%
BADD_D02500Alpelisib0.001175%
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