Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Exostosis
ADR ID BADD_A01561
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.02      Bone disorders (excl congenital and fractures)
15.02.04      Bone disorders NEC
15.02.04.005      Exostosis
Description A disorder characterized by non-neoplastic overgrowth of bone. [CTCAE] Benign hypertrophy that projects outward from the surface of bone, often containing a cartilaginous component. [MeSH]
MedDRA Code 10015688
MeSH ID D005096; D054850; D036982
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Bone spur | Calcaneal spur | Exostosis | Exostosis of orbit | Exostosis of unspecified site | Foot exostosis | Heel exostosis | Osteophytosis | Haglund deformity | Central osteophyte | Trochanteric osteophyte | Osteophyte formation | Carpometacarpal boss | Carpal bossing | Calcar calcanei | Exostoses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin--
BADD_D00066Alendronic acid0.001607%
BADD_D00165Aripiprazole--
BADD_D00195Azathioprine--
BADD_D00209Baclofen0.000104%
BADD_D00349Capecitabine--
BADD_D00356Carbamazepine0.000186%
BADD_D00410Celecoxib0.000109%
BADD_D00417Cetirizine--
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00653Diclofenac--
BADD_D00809Escitalopram--
BADD_D00898Finasteride0.000135%
BADD_D01117Ibandronic acid0.000697%
BADD_D01213Isotretinoin0.001081%
BADD_D01250Lasofoxifene--
BADD_D01253Lenalidomide0.004726%
BADD_D01260Leuprolide acetate0.001434%
BADD_D01418Methotrexate0.000944%
BADD_D01431Methylphenidate0.000041%
BADD_D01592Obeticholic acid0.002293%
BADD_D01690Pegaptanib--
BADD_D01691Pegaptanib sodium--
BADD_D01831Prednisolone0.000035%
BADD_D01966Ropinirole--
BADD_D02047Sodium oxybate0.001717%
BADD_D02058Sorafenib0.000112%
BADD_D02236Tofacitinib0.008993%
BADD_D02254Tramadol--
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