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ADR Term
ADReCS ID
MedDRA Code
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ADR Ontology
ADR Term
Anaemia macrocytic
ADR ID
BADD_A00184
ADR Hierarchy
01
Blood and lymphatic system disorders
01.03
Anaemias nonhaemolytic and marrow depression
01.03.02
Anaemias NEC
01.03.02.002
Anaemia macrocytic
14
Metabolism and nutrition disorders
14.12
Vitamin related disorders
14.12.01
Vitamin deficiencies NEC
14.12.01.002
Anaemia macrocytic
Description
Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH). [MeSH]
MedDRA Code
10002064
MeSH ID
D000748
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Anaemia macrocytic | Anemia macrocytic | Macrocytic anaemia NOS | Macrocytic anemia | Macrocytic anaemia | Anemia, Macrocytic | Anemias, Macrocytic | Macrocytic Anemia | Macrocytic Anemias
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00066
Alendronic acid
0.000110%
BADD_D00115
Amiodarone
0.000202%
BADD_D00151
Apixaban
0.000087%
BADD_D00165
Aripiprazole
0.000079%
BADD_D00195
Azathioprine
0.000470%
BADD_D00196
Azathioprine sodium
-
-
BADD_D00349
Capecitabine
0.000168%
BADD_D00356
Carbamazepine
0.000465%
BADD_D00511
Clozapine
0.004280%
BADD_D00563
Dabigatran
0.000245%
BADD_D00696
Divalproex sodium
-
-
BADD_D00768
Enalaprilat
0.002026%
BADD_D00943
Flutamide
-
-
BADD_D00979
Furosemide
0.000014%
BADD_D01083
Hydrochlorothiazide
0.000010%
BADD_D01110
Hydroxyurea
0.000336%
BADD_D01243
Lamotrigine
-
-
BADD_D01285
Levothyroxine
0.000007%
BADD_D01401
Metformin
0.000062%
BADD_D01418
Methotrexate
0.000500%
BADD_D01580
Nitrous oxide
0.000268%
BADD_D01601
Olaparib
0.000660%
BADD_D01654
Palbociclib
0.000985%
BADD_D01668
Pantoprazole
0.000049%
BADD_D01835
Pregabalin
0.000078%
BADD_D01888
Quetiapine
0.000055%
BADD_D01916
Rasagiline mesylate
-
-
BADD_D01954
Rivaroxaban
0.000127%
BADD_D02093
Sulfasalazine
-
-
BADD_D02100
Sunitinib
0.000168%
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