Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Stress cardiomyopathy
ADR ID BADD_A08842
ADR Hierarchy
02      Cardiac disorders
02.04      Myocardial disorders
02.04.01      Cardiomyopathies
02.04.01.012      Stress cardiomyopathy
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.04      Coronary necrosis and vascular insufficiency
24.04.04.026      Stress cardiomyopathy
Description A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress. [MeSH]
MedDRA Code 10066286
MeSH ID D054549
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Ampulla cardiomyopathy | Stress cardiomyopathy | Tako-Tsubo cardiomyopathy | Takotsubo syndrome | Apical ballooning syndrome | Broken heart syndrome | Takotsubo Cardiomyopathy | Cardiomyopathy, Takotsubo | Stress Cardiomyopathy | Cardiomyopathy, Stress | Tako-tsubo Cardiomyopathy | Cardiomyopathy, Tako-tsubo | Tako tsubo Cardiomyopathy | Broken Heart Syndrome | Syndrome, Broken Heart | Syndromes, Broken Heart | Takotsubo Syndrome | Transient Apical Ballooning Syndrome | Apical Ballooning Syndrome | Syndrome, Apical Ballooning | Left Ventricular Apical Ballooning Syndrome | Tako-tsubo Syndrome | Syndrome, Tako-tsubo | Syndromes, Tako-tsubo | Tako tsubo Syndrome | Tako-tsubo Syndromes
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01599Olanzapine0.000947%
BADD_D01629Osimertinib0.000224%
BADD_D01633Oxaliplatin0.000336%
BADD_D01653Paclitaxel0.000392%
BADD_D01750Phenelzine0.000062%
BADD_D01756Phentermine0.000600%
BADD_D01765Phenytoin0.000191%
BADD_D01799Ponatinib0.000112%
BADD_D01831Prednisolone0.000129%
BADD_D01834Prednisone0.000013%
BADD_D01864Propofol0.000982%
BADD_D01881Pyridostigmine0.006375%
BADD_D01959Rocuronium0.000057%
BADD_D02010Sertraline0.000025%
BADD_D02015Sevoflurane0.000268%
BADD_D02082Sufentanil0.000179%
BADD_D02098Sumatriptan0.000083%
BADD_D02100Sunitinib0.000224%
BADD_D02105Tacrolimus0.000891%
BADD_D02195Theophylline--
BADD_D02261Tranexamic acid0.010911%
BADD_D02346Venlafaxine0.000435%
BADD_D02392Zoledronic acid0.007157%
BADD_D02393Zolmitriptan0.002369%
BADD_D02416Ropivacaine0.000179%
BADD_D02428Loperamide0.000676%
BADD_D02432Glycopyrronium0.008511%
BADD_D02443Tiotropium0.000086%
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