Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Multiple organ dysfunction syndrome
ADR ID BADD_A06819
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.057      Multiple organ dysfunction syndrome
Description A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [MeSH]
MedDRA Code 10077361
MeSH ID D009102
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
MOF | Multi organ failure | Multi-organ failure | Multiorgan failure | Multiple organ failure | Multiple organ dysfunction syndrome | Multiple Organ Failure | Multiple Organ Dysfunction Syndrome | Organ Failure, Multiple | Failure, Multiple Organ | Multiple Organ Failures | MODS | Organ Dysfunction Syndrome, Multiple
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00593Decitabine0.000336%
BADD_D00594Deferasirox0.012391%
BADD_D00595Deferiprone--
BADD_D00596Deferoxamine0.001859%
BADD_D00623Dexamethasone0.003778%
BADD_D00653Diclofenac0.000205%
BADD_D00668Digoxin0.000211%
BADD_D00674Diltiazem0.000205%
BADD_D00697Dobutamine0.000127%
BADD_D00699Docetaxel--
BADD_D00704Dolutegravir sodium0.000282%
BADD_D00723Doxorubicin0.000392%
BADD_D00725Doxycycline0.000022%
BADD_D00749Efavirenz0.005505%
BADD_D00768Enalaprilat0.003039%
BADD_D00782Epinephrine0.000242%
BADD_D00784Epirubicin--
BADD_D00788Epoprostenol0.000452%
BADD_D00798Eribulin0.000168%
BADD_D00802Ertapenem0.000097%
BADD_D00854Etoposide0.000336%
BADD_D00858Everolimus0.002523%
BADD_D00861Exemestane--
BADD_D00869Famotidine0.000045%
BADD_D00873Fenofibrate0.000118%
BADD_D00902Flecainide0.000245%
BADD_D00912Fluconazole0.000202%
BADD_D00914Fludarabine0.000839%
BADD_D00931Fluorouracil0.000643%
BADD_D00956Fomepizole--
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