Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hepatocellular carcinoma
ADR ID BADD_A06706
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.07      Hepatobiliary neoplasms malignant and unspecified
16.07.02      Hepatic neoplasms malignant
16.07.02.005      Hepatocellular carcinoma
09      Hepatobiliary disorders
09.04      Hepatobiliary neoplasms
09.04.02      Malignant hepatobiliary neoplasms
09.04.02.010      Hepatocellular carcinoma
Description A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. [MeSH]
MedDRA Code 10073071
MeSH ID D006528
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hepatic fibrolamellar carcinoma non-resectable | Hepatic fibrolamellar carcinoma recurrent | Hepatic fibrolamellar carcinoma resectable | Hepatocellular carcinoma non-resectable | Hepatocellular carcinoma recurrent | Hepatocellular carcinoma resectable | Hepatoma | Hepatoma non-resectable | Hepatoma recurrent | Hepatoma resectable | Liver cell carcinoma non-resectable | Liver cell carcinoma recurrent | Liver cell carcinoma resectable | Malignant hepatoma non-resectable | Malignant hepatoma recurrent | Malignant hepatoma resectable | Carcinoma hepatocellular | Hepatocellular carcinoma | Hepatocellular carcinoma stage II | Hepatocellular carcinoma stage III | Hepatocellular carcinoma stage IV | Hepatocellular carcinoma metastatic | Hepatocellular carcinoma stage I | Carcinoma, Hepatocellular | Carcinomas, Hepatocellular | Hepatocellular Carcinomas | Liver Cell Carcinoma, Adult | Liver Cancer, Adult | Adult Liver Cancer | Adult Liver Cancers | Cancer, Adult Liver | Cancers, Adult Liver | Liver Cancers, Adult | Liver Cell Carcinoma | Carcinoma, Liver Cell | Carcinomas, Liver Cell | Cell Carcinoma, Liver | Cell Carcinomas, Liver | Liver Cell Carcinomas | Hepatocellular Carcinoma | Hepatomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00016Acamprosate--
BADD_D00044Adefovir dipivoxil0.003952%
BADD_D00178Atenolol0.000029%
BADD_D00195Azathioprine0.000627%
BADD_D00271Bicalutamide0.002109%
BADD_D00277Bisoprolol0.000471%
BADD_D00330Cabozantinib0.005652%
BADD_D00347Candesartan cilexetil0.000841%
BADD_D00415Cerivastatin--
BADD_D00474Cisplatin0.000224%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00551Cyclosporine0.000497%
BADD_D00554Cyproterone--
BADD_D00555Cyproterone acetate--
BADD_D00774Entecavir0.045763%
BADD_D00858Everolimus--
BADD_D00870Febuxostat0.000376%
BADD_D00948Fluvastatin--
BADD_D00949Fluvastatin sodium--
BADD_D01012Gemfibrozil--
BADD_D01023Glimepiride0.000064%
BADD_D01217Itraconazole0.002672%
BADD_D01242Lamivudine0.006577%
BADD_D01325Lovastatin--
BADD_D01348Mangafodipir trisodium--
BADD_D01572Nitisinone0.114278%
BADD_D01592Obeticholic acid0.002606%
BADD_D01765Phenytoin0.000574%
BADD_D01824Pravastatin--
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