| Drug Name |
Nitisinone |
| Drug ID |
BADD_D01572 |
| Description |
Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin. |
| Indications and Usage |
Used as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1. |
| Marketing Status |
approved; investigational |
| ATC Code |
A16AX04 |
| DrugBank ID |
DB00348
|
| KEGG ID |
D05177
|
| MeSH ID |
C077073
|
| PubChem ID |
115355
|
| TTD Drug ID |
D0V1UW
|
| NDC Product Code |
43235-0016; 68022-7058; 66658-110; 70505-220; 63069-071; 76055-0043; 76438-004; 13668-632; 13668-631; 63629-2234; 70505-202; 66658-120; 58159-037; 0254-3022; 63629-2235; 63069-075; 66005-0046; 70505-210; 70709-002; 24196-194; 13668-629; 13668-630; 0254-3021; 66658-102; 66658-105; 70505-205; 70709-000; 55463-0034; 63629-2233; 66658-204; 70709-005; 63069-072; 0254-3020 |
| UNII |
K5BN214699
|
| Synonyms |
nitisinone | NTBC cpd | 2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione | 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione | Orfadin |
