Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Immune reconstitution inflammatory syndrome
ADR ID BADD_A06289
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.01      Immune and associated conditions NEC
10.02.01.043      Immune reconstitution inflammatory syndrome
08      General disorders and administration site conditions
08.06      Therapeutic and nontherapeutic effects (excl toxicity)
08.06.02      Withdrawal and rebound effects
08.06.02.014      Immune reconstitution inflammatory syndrome
Description Exuberant inflammatory response towards a previously acquired or undiagnosed opportunistic infection. It is frequently seen in AIDS patients following antiretroviral treatment. [MeSH]
MedDRA Code 10065042
MeSH ID D054019
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Immune reconstitution syndrome | Immune restoration disease | Immune reconstitution inflammatory syndrome | Immune Reconstitution Inflammatory Syndrome | Immune Restoration Syndrome | Restoration Syndrome, Immune | Immune Restoration Disease | Immune Restoration Diseases | Immune Reconstitution Disease | Reconstitution Disease, Immune | Immune Reconstitution Syndrome | Immune Reconstitution Syndromes | Reconstitution Syndrome, Immune
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00008Abacavir0.008243%
BADD_D00132Amphotericin b0.000094%
BADD_D00176Atazanavir0.001804%
BADD_D00195Azathioprine0.001410%
BADD_D00405Ceftriaxone0.020054%
BADD_D00474Cisplatin0.000112%
BADD_D00480Clarithromycin0.000447%
BADD_D00560Cytarabine0.000224%
BADD_D00580Dapsone0.000367%
BADD_D00586Darunavir--
BADD_D00587Darunavir ethanolate--
BADD_D00593Decitabine0.000112%
BADD_D00623Dexamethasone0.000145%
BADD_D00680Dimethyl fumarate0.001600%
BADD_D00704Dolutegravir sodium0.001976%
BADD_D00723Doxorubicin0.000336%
BADD_D00749Efavirenz0.023856%
BADD_D00766Emtricitabine0.019598%
BADD_D00794Ergocalciferol0.000684%
BADD_D00857Etravirine--
BADD_D00912Fluconazole0.000360%
BADD_D01217Itraconazole0.004008%
BADD_D01242Lamivudine0.004554%
BADD_D01557Nevirapine0.002652%
BADD_D01831Prednisolone0.000087%
BADD_D01834Prednisone0.000045%
BADD_D01905Raltegravir0.009889%
BADD_D01935Rifabutin0.021874%
BADD_D01952Ritonavir0.001102%
BADD_D02068Stavudine0.000282%
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