Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Disease progression
ADR ID BADD_A05989
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.038      Disease progression
Description Death due to disease progression that cannot be attributed to a CTCAE term associated with Grade 5. [CTCAE] The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis. [MeSH]
MedDRA Code 10061818
MeSH ID D018450
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Disease progression NOS | Disease progression | Disease Progression | Disease Progressions | Progression, Disease | Progressions, Disease | Disease Exacerbation
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00466Cilostazol0.000300%
BADD_D00474Cisplatin0.002988%
BADD_D00495Clofarabine0.000168%
BADD_D00501Clonazepam--
BADD_D00513Cobimetinib0.000112%
BADD_D00535Crizotinib0.070067%
BADD_D00551Cyclosporine0.002343%
BADD_D00556Cysteamine0.000671%
BADD_D00561Cytarabine hydrochloride--
BADD_D00566Dabrafenib0.002697%
BADD_D00568Dacarbazine0.000168%
BADD_D00593Decitabine0.001791%
BADD_D00594Deferasirox0.060717%
BADD_D00596Deferoxamine0.003098%
BADD_D00599Degarelix--
BADD_D00612Desipramine0.007437%
BADD_D00623Dexamethasone0.003444%
BADD_D00633Dexrazoxane--
BADD_D00699Docetaxel--
BADD_D00723Doxorubicin0.007063%
BADD_D00759Eltrombopag0.003681%
BADD_D00775Enzalutamide0.015783%
BADD_D00784Epirubicin0.001007%
BADD_D00788Epoprostenol0.001645%
BADD_D00800Erlotinib0.030836%
BADD_D00854Etoposide0.000750%
BADD_D00858Everolimus0.035011%
BADD_D00861Exemestane0.085326%
BADD_D00914Fludarabine0.000616%
BADD_D00931Fluorouracil0.004007%
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