Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Intervertebral disc degeneration
ADR ID BADD_A05832
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.10      Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)
15.10.01      Intervertebral disc disorders NEC
15.10.01.002      Intervertebral disc degeneration
Description Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates. [MeSH]
MedDRA Code 10061246
MeSH ID D055959
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cervical disc degeneration | Degeneration of cervical intervertebral disc | Degeneration of intervertebral disc, site unspecified | Degeneration of lumbar or lumbosacral intervertebral disc | Degeneration of thoracic or lumbar intervertebral disc | Degeneration of thoracic or thoracolumbar intervertebral disc | Intervertebral disc degeneration NOS | Lumbar disc degeneration | Thoracic disc degeneration | Intervertebral chondrosis | Intervertebral disc degeneration | Intervertebral disc vacuum phenomenon | Degenerative disc disease | Intervertebral disc desiccation | Discarthrosis | Intervertebral Disc Degeneration | Degeneration, Intervertebral Disc | Degenerations, Intervertebral Disc | Disc Degeneration, Intervertebral | Disc Degenerations, Intervertebral | Intervertebral Disc Degenerations | Intervertebral Disk Degeneration | Degeneration, Intervertebral Disk | Degenerations, Intervertebral Disk | Disk Degeneration, Intervertebral | Disk Degenerations, Intervertebral | Intervertebral Disk Degenerations | Disk Degeneration | Degeneration, Disk | Degenerations, Disk | Disk Degenerations | Disk Degradation | Degradation, Disk | Degradations, Disk | Disk Degradations | Disc Degeneration | Degeneration, Disc | Degenerations, Disc | Disc Degenerations | Disc Degradation | Degradation, Disc | Degradations, Disc | Disc Degradations | Degenerative Intervertebral Discs | Degenerative Intervertebral Disc | Disc, Degenerative Intervertebral | Discs, Degenerative Intervertebral | Intervertebral Disc, Degenerative | Intervertebral Discs, Degenerative | Degenerative Intervertebral Disks | Degenerative Intervertebral Disk | Disk, Degenerative Intervertebral | Disks, Degenerative Intervertebral | Intervertebral Disk, Degenerative | Intervertebral Disks, Degenerative
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00044Adefovir dipivoxil0.000282%
BADD_D00066Alendronic acid0.002730%
BADD_D00165Aripiprazole0.000119%
BADD_D00277Bisoprolol0.000471%
BADD_D00405Ceftriaxone0.004457%
BADD_D00410Celecoxib0.000254%
BADD_D00621Desvenlafaxine0.000695%
BADD_D00680Dimethyl fumarate0.001000%
BADD_D00775Enzalutamide0.000334%
BADD_D00879Fentanyl0.000211%
BADD_D00898Finasteride0.000490%
BADD_D01119Ibrutinib--
BADD_D01136Imatinib0.000168%
BADD_D01213Isotretinoin0.001415%
BADD_D01252Leflunomide0.000643%
BADD_D01285Levothyroxine0.000013%
BADD_D01418Methotrexate--
BADD_D01533Naproxen0.000019%
BADD_D01567Nilotinib0.000806%
BADD_D01645Oxycodone0.000093%
BADD_D01834Prednisone--
BADD_D01835Pregabalin0.000648%
BADD_D01966Ropinirole--
BADD_D02029Sitagliptin0.000106%
BADD_D02047Sodium oxybate0.002843%
BADD_D02100Sunitinib0.000246%
BADD_D02107Tafamidis0.001346%
BADD_D02154Tenofovir0.001939%
BADD_D02165Teriflunomide0.000940%
BADD_D02170Testosterone0.000245%
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