Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone
Drug ID BADD_D01645
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D05312
MeSH ID D010098
PubChem ID 5284603
TTD Drug ID D07WPQ
NDC Product Code 68071-5055; 0904-7180; 65162-047; 24510-115; 24510-130; 67651-0304; 65162-050; 71335-1023; 67651-0306; 67651-0305; 71335-0981; 24510-140; 71335-1080; 65162-051; 24510-120; 65162-048; 67877-625; 71335-0677; 65162-049; 67651-0303; 24510-110; 67877-623; 0904-6966; 67651-0302
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H21NO4
CAS Registry Number 76-42-6
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.001300%Not Available
Abdominal distension07.01.04.0010.000557%
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.0030.000975%
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Abscess11.01.08.0010.000093%Not Available
Accidental overdose12.06.03.002--Not Available
Acidosis14.01.03.0020.000139%
Acne23.02.01.001--Not Available
Activated partial thromboplastin time prolonged13.01.02.0010.000093%
Acute abdomen07.01.06.0150.000093%Not Available
Acute pulmonary oedema02.05.02.004; 22.01.03.0050.000139%Not Available
Acute respiratory distress syndrome22.01.03.0010.000097%
Acute respiratory failure14.01.04.004; 22.02.06.001--Not Available
Addison's disease05.01.02.006; 10.04.08.008; 14.11.01.025--Not Available
Adrenal insufficiency05.01.02.001; 14.11.01.0040.000232%
Aggression19.05.01.001--Not Available
Agitation17.02.05.012; 19.06.02.0010.000882%
Akathisia17.01.02.002; 19.06.02.0060.000186%
Alanine aminotransferase increased13.03.01.003--
Alcohol abuse19.07.02.007--Not Available
Alcoholism19.07.02.001--Not Available
Altered state of consciousness17.02.04.001; 19.07.01.0030.000418%Not Available
Amblyopia06.02.01.001--Not Available
Amenorrhoea05.05.01.002; 21.01.02.001--
Amnesia17.03.02.001; 19.20.01.0010.000603%
Anaemia01.03.02.001--
Anaesthetic complication pulmonary12.02.12.007; 22.02.07.0050.000139%Not Available
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
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