Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Metastases to central nervous system
ADR ID BADD_A05661
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.22      Metastases
16.22.02      Metastases to specified sites
16.22.02.004      Metastases to central nervous system
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.10      Nervous system disorders NEC
17.02.10.013      Metastases to central nervous system
Description Not Available
MedDRA Code 10059282
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Brain metastases | Brain secondaries | Metastases to brain | Secondary malignant neoplasm of brain and spinal cord | Cerebellar metastases | Metastases to central nervous system | Secondary malignant neoplasm of brain
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.001001%
BADD_D00047Afatinib0.007723%
BADD_D00193Axitinib--
BADD_D00318Busulfan--
BADD_D00330Cabozantinib0.001612%
BADD_D00349Capecitabine0.001198%
BADD_D00364Carboplatin0.001231%
BADD_D00414Ceritinib0.003022%
BADD_D00474Cisplatin0.000336%
BADD_D00479Cladribine0.000153%
BADD_D00511Clozapine--
BADD_D00535Crizotinib0.001041%
BADD_D00566Dabrafenib0.001198%
BADD_D00623Dexamethasone0.000654%
BADD_D00699Docetaxel--
BADD_D00723Doxorubicin0.000504%
BADD_D00775Enzalutamide0.001502%
BADD_D00798Eribulin0.000448%
BADD_D00800Erlotinib0.001679%
BADD_D00858Everolimus0.002125%
BADD_D00978Fulvestrant0.002169%
BADD_D01008Gefitinib0.002462%
BADD_D01009Gemcitabine0.000224%
BADD_D01096Hydromorphone--
BADD_D01133Ifosfamide--
BADD_D01136Imatinib0.000582%
BADD_D01248Lapatinib0.000862%
BADD_D01254Lenvatinib0.000224%
BADD_D01257Letrozole0.001317%
BADD_D01258Leucovorin0.001239%
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