Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Major depression
ADR ID BADD_A05530
ADR Hierarchy
19      Psychiatric disorders
19.15      Depressed mood disorders and disturbances
19.15.01      Depressive disorders
19.15.01.003      Major depression
Description An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. [MeSH]
MedDRA Code 10057840
MeSH ID D003866; D003865
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Depression endogenous | Depression psychotic | Depressive type psychosis | Endogenous depression | Involutional depression | Involutional melancholia | Major depressive disorder NOS | Major depressive disorder, recurrent episode | Major depressive disorder, recurrent episode, in full remission | Major depressive disorder, recurrent episode, in partial or unspecified remission | Major depressive disorder, recurrent episode, mild degree | Major depressive disorder, recurrent episode, moderate degree | Major depressive disorder, recurrent episode, severe degree, specified as with psychotic behavior | Major depressive disorder, recurrent episode, severe degree, specified as with psychotic behaviour | Major depressive disorder, recurrent episode, severe degree, without mention of psychotic behavior | Major depressive disorder, recurrent episode, unspecified degree | Major depressive disorder, single episode | Major depressive disorder, single episode in full remission | Major depressive disorder, single episode, in partial or unspecified remission | Major depressive disorder, single episode, mild degree | Major depressive disorder, single episode, moderate degree | Major depressive disorder, single episode, severe degree, specified as with psychotic behavior | Major depressive disorder, single episode, severe degree, without mention of psychotic behavior | Major depressive disorder, single episode, unspecified degree | Major depressive illness | Melancholia | Melancholic depression | Psychosis depressive | Psychotic depression | Major depressive disorder with melancholic features | Major depression | Major depressive disorder aggravated | Major depressive disorder | Clinical depression | Depressive Disorder | Depressive Disorders | Disorder, Depressive | Disorders, Depressive | Neurosis, Depressive | Depressive Neuroses | Depressive Neurosis | Neuroses, Depressive | Depression, Endogenous | Depressions, Endogenous | Endogenous Depression | Endogenous Depressions | Depressive Syndrome | Depressive Syndromes | Syndrome, Depressive | Syndromes, Depressive | Depression, Neurotic | Depressions, Neurotic | Neurotic Depression | Neurotic Depressions | Melancholias | Unipolar Depression | Depression, Unipolar | Depressions, Unipolar | Unipolar Depressions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00039Acyclovir--
BADD_D00066Alendronic acid0.000286%
BADD_D00085Alprazolam--
BADD_D00156Apremilast--
BADD_D00165Aripiprazole0.000357%
BADD_D00180Atomoxetine--
BADD_D00181Atomoxetine hydrochloride--
BADD_D00209Baclofen0.000104%
BADD_D00284Bortezomib0.000112%
BADD_D00312Bupropion0.000028%
BADD_D00475Citalopram0.000019%
BADD_D00476Citalopram hydrobromide--
BADD_D00501Clonazepam0.000030%
BADD_D00511Clozapine0.013452%
BADD_D00555Cyproterone acetate--
BADD_D00621Desvenlafaxine0.000446%
BADD_D00623Dexamethasone0.000145%
BADD_D00680Dimethyl fumarate0.002600%
BADD_D00686Diphenhydramine0.000201%
BADD_D00706Donepezil--
BADD_D00707Donepezil hydrochloride--
BADD_D00734Duloxetine0.000192%
BADD_D00755Eletriptan--
BADD_D00756Eletriptan hydrobromide--
BADD_D00766Emtricitabine--
BADD_D00788Epoprostenol--
BADD_D00809Escitalopram0.000057%
BADD_D00841Ethambutol0.001027%
BADD_D00898Finasteride0.001285%
BADD_D00932Fluoxetine0.000102%
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